Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNE1 | P15382 | 12/20 | 1.00 |
| ▸ | KCNQ1 | P51787 | 12/20 | 1.00 |
| ▸ | MEN1 | O00255 | 1/20 | 0.86 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.86 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.86 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.86 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.86 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.86 |
| ▸ | KCND3 | Q9UK17 | 1/20 | 0.86 |
| ▸ | ABCB1 | P08183 | 7/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6561052 | 1.00 | KCNE1 (1.00) | KCNE1KCNQ1MEN1CYP1A2CYP3A4 | |
| SCHEMBL6561056 | 1.00 | KCNE1 (1.00) | KCNE1KCNQ1MEN1CYP1A2CYP3A4 | |
| SCHEMBL4292069 | 0.93 | KCNE1 (1.00) | KCNE1KCNQ1MEN1CYP1A2CYP3A4 | |
| SCHEMBL29389863 | 0.93 | KCNE1 (1.00) | KCNE1KCNQ1MEN1CYP1A2CYP3A4 | |
| SCHEMBL4292061 | 0.93 | KCNE1 (1.00) | KCNE1KCNQ1MEN1CYP1A2CYP3A4 | |
| SCHEMBL4292064 | 0.93 | KCNE1 (1.00) | KCNE1KCNQ1MEN1CYP1A2CYP3A4 | |
| SCHEMBL6559939 | 0.84 | KCNE1 (0.79) | KCNE1KCNQ1MEN1CYP1A2CYP3A4 | |
| SCHEMBL6559944 | 0.84 | KCNE1 (0.79) | KCNE1KCNQ1MEN1CYP1A2CYP3A4 | |
| SCHEMBL6559948 | 0.84 | KCNE1 (0.79) | KCNE1KCNQ1MEN1CYP1A2CYP3A4 | |
| SCHEMBL6560803 | 0.83 | KCNE1 (0.78) | KCNE1KCNQ1MEN1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0807629-B1 | Sulfonamido substituted chromane derivatives, method for their preparation, their use as medicaments or diagnostic agents aswell as medicaments containing them | AVENTIS PHARMA GMBH (DE) | 2004-03-03 | — | — | EP | disclosed |
| EP-0807629-A1 | Sulfonamido substituted chromane derivatives, method for their preparation, their use as medicaments or diagnostic agents aswell as medicaments containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-11-19 | — | — | EP | disclosed |