SCHEMBL6561060

SCHEMBL6561060

CNC(=O)N(CC(C)C)CC(C)C

nearest known ligand 0.50

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CA12 O43570 4/20 0.50
CA1 P00915 4/20 0.50
CA2 P00918 4/20 0.50
CA9 Q16790 4/20 0.50
KMT2A Q03164 1/20 0.38
MME P08473 4/20 0.36
ACE P12821 4/20 0.36
MLYCD O95822 2/20 0.35
LMNA P02545 1/20 0.34
HDAC1 Q13547 1/20 0.33
HDAC6 Q9UBN7 1/20 0.33
ALDH1A1 P00352 1/20 0.33
FPR1 P21462 1/20 0.33
HSD17B10 Q99714 1/20 0.33
MMP1 P03956 1/20 0.32
MMP8 P22894 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL967201 0.89 CA12 (0.45) CA12CA1CA2CA9KMT2A
SCHEMBL965496 0.78 CA1 (0.38) CA12CA1CA2CA9KMT2A
SCHEMBL19027666 0.76 CA1 (0.37) CA12CA1CA2CA9KMT2A
SCHEMBL27750762 0.76 CYP2D6 (0.50) CA12CA1CA2CA9KMT2A
SCHEMBL28280149 0.73 CA12 (0.43) CA12CA1CA2CA9KMT2A
SCHEMBL30876522 0.73 CA12 (0.43) CA12CA1CA2CA9KMT2A
SCHEMBL28292267 0.72 CA12 (0.33) CA12CA1CA2CA9
SCHEMBL1547062 0.70 CA1 (0.56) CA12CA1CA2CA9MLYCD
SCHEMBL42386 0.70
SCHEMBL2886330 0.70 CA1 (0.56) CA12CA1CA2CA9MLYCD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1094095-B1 Surface tension reduction with n,n,n'-trialkyl ureas AIR PROD & CHEM (US) 2004-07-28 EP claimed
US-6281170-B1 Surface tension reduction with N,N,N'-trialkkyl ureas AIR PRODUCTS AND CHEMICALS, INC. 2001-08-28 US claimed
EP-1094095-A1 Surface tension reduction with n,n,n'-trialkyl ureas AIR PRODUCTS AND CHEMICALS, INC. (US) 2001-04-25 EP claimed
EP-1094095-B1 Surface tension reduction with n,n,n'-trialkyl ureas AIR PROD & CHEM (US) 2004-07-28 EP disclosed
US-6281170-B1 Surface tension reduction with N,N,N'-trialkkyl ureas AIR PRODUCTS AND CHEMICALS, INC. 2001-08-28 US disclosed
EP-1094095-A1 Surface tension reduction with n,n,n'-trialkyl ureas AIR PRODUCTS AND CHEMICALS, INC. (US) 2001-04-25 EP disclosed