⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2918727 | 0.85 | — | — | |
| SCHEMBL971151 | 0.85 | CA12 (0.44) | — | |
| SCHEMBL19027653 | 0.83 | ROCK2 (0.35) | — | |
| SCHEMBL967106 | 0.81 | CA12 (0.55) | — | |
| SCHEMBL14355322 | 0.81 | LMNA (0.33) | — | |
| SCHEMBL967201 | 0.81 | CA12 (0.45) | — | |
| SCHEMBL18056397 | 0.81 | PRMT3 (0.37) | — | |
| SCHEMBL19027655 | 0.81 | LMNA (0.33) | — | |
| SCHEMBL965925 | 0.79 | MLYCD (0.34) | — | |
| SCHEMBL969697 | 0.79 | LMNA (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 116 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023212693-A1 | ALLOSTERIC CHROMENONE INHIBITORS OF PHOSPHOINOSITIDE 3-KINASE (PI3K) FOR THE TREATMENT OF DISEASE | PETRA PHARMA CORPORATION (US) | 2023-11-02 | — | — | WO | disclosed |
| US-20230159743-A1 | HEAT-CURABLE EPOXY RESIN COMPOSITION AND HEAT-CURABLE EPOXY RESIN SHEET | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2023-05-25 | — | — | US | disclosed |
| WO-2023091644-A2 | HSD17B13-RELATED DOUBLE STRANDED OLIGONUCLEOTIDE COMPOSITIONS AND METHODS RELATING THERETO | WAVE LIFE SCIENCES LTD. (SG) | 2023-05-25 | — | — | WO | disclosed |
| US-20230147458-A1 | IMIDAZOPYRIDAZINE IL-17 INHIBITOR COMPOUNDS | JANSSEN RESEARCH & DEVELOPMENT, LLC | 2023-05-11 | — | — | US | disclosed |
| WO-2023049218-A1 | DOUBLE STRANDED OLIGONUCLEOTIDE COMPOSITIONS AND METHODS RELATING THERETO | WAVE LIFE SCIENCES LTD. (SG) | 2023-03-30 | — | — | WO | disclosed |
| WO-2021237223-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2021-11-25 | — | — | WO | disclosed |
| US-11147272-B2 | Pyridone compounds and agricultural and horticultural fungicides comprising the same as active ingredients | MITSUI CHEMICALS ARGRO, INC. (JP) | 2021-10-19 | — | — | US | disclosed |
| WO-2021181307-A1 | PHOTOCHROMIC POLYDIORGANOSILOXANE VINYLIC CROSSLINKERS | ALCON INC. (CH) | 2021-09-16 | — | — | WO | disclosed |
| US-11000038-B2 | Pyridone compounds and agricultural and horticultural fungicides containing the same as active ingredients | MITSUI CHEMICALS AGRO, INC. (JP) | 2021-05-11 | — | — | US | disclosed |
| US-10808102-B2 | Thermosetting epoxy resin sheet for encapsulating semiconductor, semiconductor equipment, and method for manufacturing the same | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2020-10-20 | — | — | US | disclosed |
| US-5594003-A | HYPOTENSIVE AGENTS | DR. KARL THOMAE GMBH (DE) | 1997-01-14 | — | — | US | disclosed |
| US-5591762-A | HYPOTENSIVE AGENTS | DR. KARL THOMAE GMBH (DE) | 1997-01-07 | — | — | US | disclosed |
| WO-1996037471-A1 | N-AMINOPYRIDONE DERIVATIVES AND THEIR USE AS HERBICIDES | BASF AKTIENGESELLSCHAFT (DE) | 1996-11-28 | — | — | WO | disclosed |
| US-5541229-A | ANGIOITENSIN II ANTAGONIST AS HYPOTENSIVE AGENTS, ANTIISCHEMIC AGENTS AND CARDIOVASCULAR DISORDERS | DR. KARL THOMAE GMBH (DE) | 1996-07-30 | — | — | US | disclosed |
| US-5459147-A | Angeotensin-antagonistic effects; hypotensive, antiischemic, and antidiabetic agents, treating glaucoma | DR. KARL THOMAE GMBH (DE) | 1995-10-17 | — | — | US | disclosed |
| US-4371544-A | ANTIINFLAMMATORY AGENTS, ANALGESTICS | TAIHO PHARMACEUTICAL COMPANY LIMITED (JP) | 1983-02-01 | — | — | US | disclosed |
| US-4278672-A | ANALGESICS, ANTIINFLAMMATORY AGENTS | TAIHO PHARMACEUTICAL COMPANY, LIMITED (JP) | 1981-07-14 | — | — | US | disclosed |
| US-4239761-A | VIRICIDES | ASTA-WERKE AKTIENGESELLSCHAFT, CHEMISCHE FABRIK (DE) | 1980-12-16 | — | — | US | disclosed |
| EP-0008696-A1 | Basically substituted urea compounds, process for producing the same and pharmaceutical compositions containing the same | Asta-Werke Aktiengesellschaft Chemische Fabrik (DE) | 1980-03-19 | — | — | EP | disclosed |
| US-4014876-A | HYPOGLYCEMIC | SHIONOGI & CO., LTD. (JA) | 1977-03-29 | — | — | US | disclosed |