Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 13/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 12/20 | 0.44 |
| ▸ | GAA | P10253 | 8/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | GLA | P06280 | 4/20 | 0.44 |
| ▸ | CASP1 | P29466 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6561151 | 1.00 | MAPT (0.47) | MAPTALDH1A1KDM4EGAAHPGD | |
| SCHEMBL3353464 | 0.82 | MAPT (0.68) | MAPTALDH1A1KDM4EGAAHPGD | |
| SCHEMBL6559530 | 0.80 | KDM4E (0.49) | MAPTALDH1A1KDM4EGAAHPGD | |
| SCHEMBL6559535 | 0.80 | KDM4E (0.49) | MAPTALDH1A1KDM4EGAAHPGD | |
| SCHEMBL6561063 | 0.78 | MAPT (0.43) | MAPTALDH1A1KDM4EGAAHPGD | |
| SCHEMBL6561065 | 0.78 | MAPT (0.43) | MAPTALDH1A1KDM4EGAAHPGD | |
| SCHEMBL6561022 | 0.78 | BCL2L1 (0.43) | MAPTALDH1A1KDM4EGAAHPGD | |
| SCHEMBL6561017 | 0.78 | BCL2L1 (0.43) | MAPTALDH1A1KDM4EGAAHPGD | |
| SCHEMBL2812534 | 0.76 | RXRA (0.52) | MAPTALDH1A1KDM4EGAAHPGD | |
| SCHEMBL6559505 | 0.76 | KDM4E (0.61) | MAPTALDH1A1KDM4EGAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0807629-B1 | Sulfonamido substituted chromane derivatives, method for their preparation, their use as medicaments or diagnostic agents aswell as medicaments containing them | AVENTIS PHARMA GMBH (DE) | 2004-03-03 | — | — | EP | disclosed |
| US-6191164-B1 | POTASSIUM CHANNEL MODULATORS; ANTIULCER AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 2001-02-20 | — | — | US | disclosed |
| EP-0807629-A1 | Sulfonamido substituted chromane derivatives, method for their preparation, their use as medicaments or diagnostic agents aswell as medicaments containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-11-19 | — | — | EP | disclosed |