Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGA4 | P13612 | 20/20 | 0.63 |
| ▸ | ITGB1 | P05556 | 19/20 | 0.63 |
| ▸ | ITGA2 | P17301 | 1/20 | 0.63 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6561162 | 1.00 | ITGA4 (0.63) | ITGA4ITGB1ITGA2ITGB7 | |
| SCHEMBL6561172 | 1.00 | ITGA4 (0.63) | ITGA4ITGB1ITGA2ITGB7 | |
| SCHEMBL6561759 | 0.82 | ITGB1 (0.54) | ITGA4ITGB1ITGA2ITGB7 | |
| SCHEMBL6563443 | 0.82 | ITGA4 (0.59) | ITGA4ITGB1ITGA2ITGB7 | |
| SCHEMBL6561757 | 0.82 | ITGB1 (0.54) | ITGA4ITGB1ITGA2ITGB7 | |
| SCHEMBL6561736 | 0.82 | ITGB1 (0.62) | ITGA4ITGB1ITGA2ITGB7 | |
| SCHEMBL6561603 | 0.82 | ITGB1 (0.62) | ITGA4ITGB1ITGA2ITGB7 | |
| SCHEMBL6561577 | 0.82 | ITGB1 (0.62) | ITGA4ITGB1ITGA2ITGB7 | |
| SCHEMBL6561188 | 0.82 | ITGB1 (0.62) | ITGA4ITGB1ITGA2ITGB7 | |
| SCHEMBL6561185 | 0.82 | ITGB1 (0.62) | ITGA4ITGB1ITGA2ITGB7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1144365-B1 | INHIBITORS OF ALPHA-4 BETA-1 MEDIATED CELL ADHESION | TANABE SEIYAKU CO (JP) | 2004-03-17 | — | — | EP | disclosed |
| EP-1144365-A3 | INHIBITORS OF ALPHA-4 BETA-1 MEDIATED CELL ADHESION | TANABE SEIYAKU CO., LTD. (JP) | 2003-07-09 | — | — | EP | disclosed |
| EP-1144365-A2 | INHIBITORS OF ALPHA-4 BETA-1 MEDIATED CELL ADHESION | TANABE SEIYAKU CO., LTD. (JP) | 2001-10-17 | — | — | EP | disclosed |
| WO-2000037429-A2 | INHIBITORS OF α4β1 MEDIATED CELL ADHESION | TANABE SEIYAKU CO., LTD. (JP) | 2000-06-29 | — | — | WO | disclosed |