SCHEMBL6561168

SCHEMBL6561168

COc1cc(C(=O)Oc2ccc(C(=O)O)cc2)ccc1O

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.71
KMT2A Q03164 4/20 0.58
MEN1 O00255 2/20 0.58
RAB9A P51151 2/20 0.58
SLC22A6 Q4U2R8 1/20 0.58
SLC22A8 Q8TCC7 1/20 0.58
HSD17B2 P37059 1/20 0.57
KDM4E B2RXH2 2/20 0.55
POLB P06746 2/20 0.55
HDAC6 Q9UBN7 1/20 0.55
CXCL12 P48061 1/20 0.53
CA1 P00915 2/20 0.51
CA2 P00918 2/20 0.51
CA12 O43570 1/20 0.51
CA4 P22748 1/20 0.51
CA6 P23280 1/20 0.51
CA7 P43166 1/20 0.51
TPMT P51580 1/20 0.51
CA9 Q16790 1/20 0.51
CA14 Q9ULX7 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18121564 0.91 KMT2A (0.62) HTTKMT2AMEN1RAB9ASLC22A6
SCHEMBL11583873 0.89 HTT (0.63) HTTKMT2AMEN1RAB9ASLC22A6
SCHEMBL768186 0.89 KMT2A (0.60) HTTKMT2AMEN1RAB9ASLC22A6
SCHEMBL7763155 0.88 KMT2A (0.58) HTTKMT2AMEN1RAB9ASLC22A6
SCHEMBL2790416 0.88 KMT2A (0.67) HTTKMT2AMEN1RAB9ASLC22A6
SCHEMBL14996370 0.88 HSD17B2 (0.61) HTTKMT2AMEN1RAB9ASLC22A6
SCHEMBL357407 0.85 HTT (0.76) HTTKMT2AMEN1RAB9ASLC22A6
SCHEMBL8756081 0.84 KMT2A (0.61) HTTKMT2AMEN1RAB9ASLC22A6
SCHEMBL768259 0.84 HSD17B2 (0.60) HTTKMT2AMEN1RAB9ASLC22A6
SCHEMBL6561169 0.84 TTR (0.68) HTTKMT2AMEN1KDM4ECA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1239734-A4 ANTIOXIDANT COMPOSITIONS EXTRACTED FROM OLIVES AND OLIVE BY-PRODUCTS USANA INC (US) 2004-07-14 EP disclosed
EP-1239734-A1 ANTIOXIDANT COMPOSITIONS EXTRACTED FROM OLIVES AND OLIVE BY-PRODUCTS Usana, Inc. (US) 2002-09-18 EP disclosed
WO-2001045514-A1 ANTIOXIDANT COMPOSITIONS EXTRACTED FROM OLIVES AND OLIVE BY-PRODUCTS USANA, INC. (US) 2001-06-28 WO disclosed