(Phenylsulfonyl)Benzene

(Phenylsulfonyl)Benzene

SCHEMBL6561396

O=C(O)c1ccc(-c2ccc(C(=O)O)cc2)cc1.O=S(=O)(c1ccccc1)c1ccccc1

nearest known ligand 0.84

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 5/20 0.60
CA1 P00915 5/20 0.60
CA2 P00918 5/20 0.60
CA9 Q16790 5/20 0.60
CA14 Q9ULX7 5/20 0.60
HTR6 P50406 1/20 0.58
EGFR P00533 1/20 0.53
DAO P14920 1/20 0.52
TSHR P16473 1/20 0.52
NAPRT Q6XQN6 1/20 0.52
BCL2L1 Q07817 1/20 0.52
BAD Q92934 1/20 0.52
SRD5A2 P31213 2/20 0.52
MEN1 O00255 1/20 0.51
HPGD P15428 1/20 0.51
KMT2A Q03164 1/20 0.51
CES2 O00748 1/20 0.50
CES1 P23141 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
CA3 P07451 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL165237 0.91 HTR6 (0.64) CA12CA1CA2CA9CA14
SCHEMBL9852574 0.91 CA12 (0.70) CA12CA1CA2CA9CA14
SCHEMBL22349 0.84 CA1 (0.67) CA12CA1CA2CA9CA14
SCHEMBL2917437 0.84 CA1 (0.67) CA12CA1CA2CA9CA14
SCHEMBL5581302 0.84 CA1 (0.67) CA12CA1CA2CA9CA14
Hydrochloric Acid SCHEMBL1338222 0.82 CA1 (0.64) CA12CA1CA2CA9CA14
SCHEMBL9131940 0.82 CA1 (0.64) CA12CA1CA2CA9CA14
SCHEMBL9132774 0.82 CA1 (0.64) CA12CA1CA2CA9CA14
SCHEMBL9134104 0.82 CA1 (0.64) CA12CA1CA2CA9CA14
SCHEMBL9134718 0.82 CA1 (0.64) CA12CA1CA2CA9CA14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0976774-B1 Method for producing polyamides KURARAY CO (JP) 2004-03-24 EP disclosed