Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 4/20 | 0.37 |
| ▸ | CA9 | Q16790 | 4/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 7/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 4/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11746006 | 0.89 | CA12 (0.42) | CA12CA9CA1CA2CHRM2 | |
| SCHEMBL2290500 | 0.89 | CA12 (0.42) | CA12CA9CA1CA2CHRM2 | |
| SCHEMBL11548379 | 0.89 | CA12 (0.42) | CA12CA9CA1CA2CHRM2 | |
| SCHEMBL11548381 | 0.89 | CA12 (0.42) | CA12CA9CA1CA2CHRM2 | |
| SCHEMBL254386 | 0.89 | CA12 (0.42) | CA12CA9CA1CA2CHRM2 | |
| SCHEMBL19464089 | 0.81 | CA12 (0.38) | CA12CA9CA1CA2CHRM2 | |
| SCHEMBL8490943 | 0.79 | CA12 (0.43) | CA12CA9CA1CA2CHRM2 | |
| SCHEMBL11835924 | 0.78 | CA12 (0.40) | CA12CA9CA1CA2TSHR | |
| SCHEMBL11835919 | 0.78 | CA12 (0.40) | CA12CA9CA1CA2TSHR | |
| SCHEMBL9600313 | 0.78 | CA12 (0.40) | CA12CA9CA1CA2CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6824982-B1 | High-throughput-screening method for determining enantioselectivity | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 2004-11-30 | — | — | US | disclosed |
| EP-1165834-B1 | HIGH THROUGHPUT SCREENING METHOD FOR DETERMINING ENANTIOSELECTIVITY | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 2004-09-15 | — | — | EP | disclosed |