Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 4/20 | 0.40 |
| ▸ | CA9 | Q16790 | 4/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL254386 | 0.87 | CA12 (0.42) | CA12CA9CA1CA2CHRM2 | |
| SCHEMBL2290500 | 0.87 | CA12 (0.42) | CA12CA9CA1CA2CHRM2 | |
| SCHEMBL11746006 | 0.87 | CA12 (0.42) | CA12CA9CA1CA2CHRM2 | |
| SCHEMBL11548379 | 0.87 | CA12 (0.42) | CA12CA9CA1CA2CHRM2 | |
| SCHEMBL11548381 | 0.87 | CA12 (0.42) | CA12CA9CA1CA2CHRM2 | |
| SCHEMBL19464089 | 0.83 | CA12 (0.38) | CA12CA9CA1CA2ALDH1A1 | |
| SCHEMBL15750146 | 0.83 | SLC6A4 (0.33) | — | |
| SCHEMBL11835919 | 0.80 | CA12 (0.40) | CA12CA9CA1CA2TSHR | |
| SCHEMBL9599191 | 0.80 | — | — | |
| SCHEMBL11835924 | 0.80 | CA12 (0.40) | CA12CA9CA1CA2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0489876-A1 | SYNTHESIS OF CYCLOPENTENE DERIVATIVES | GLAXO INC. (US) | 1992-06-17 | — | — | EP | claimed |
| WO-1991015447-A1 | SYNTHESIS OF CYCLOPENTENE DERIVATIVES | GLAXO INC. (US) | 1991-10-17 | — | — | WO | claimed |
| US-5241069-A | Carbonate intermediates for the synthesis of purine substituted cyclopentene derivatives | GLAXO INC. (US) | 1993-08-31 | — | — | US | disclosed |
| US-5126452-A | SYNTHESIS OF PURINE SUBSTITUTED CYCLOPENTENE DERIVATIVES | GLAXO INC. (US) | 1992-06-30 | — | — | US | disclosed |
| EP-0489876-A1 | SYNTHESIS OF CYCLOPENTENE DERIVATIVES | GLAXO INC. (US) | 1992-06-17 | — | — | EP | disclosed |
| WO-1991015447-A1 | SYNTHESIS OF CYCLOPENTENE DERIVATIVES | GLAXO INC. (US) | 1991-10-17 | — | — | WO | disclosed |
| US-5057630-A | SYNTHESIS OF CYCLOPENTENE DERIVATIVES | GLAXO INC. (US) | 1991-10-15 | — | — | US | disclosed |