Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 19/20 | 0.82 |
| ▸ | PPARG | P37231 | 17/20 | 0.82 |
| ▸ | PPARA | Q07869 | 17/20 | 0.82 |
| ▸ | NR1H2 | P55055 | 9/20 | 0.69 |
| ▸ | NR1H3 | Q13133 | 9/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6561754 | 0.92 | PPARD (0.69) | PPARDPPARGPPARANR1H2NR1H3 | |
| SCHEMBL6561585 | 0.90 | PPARD (1.00) | PPARDPPARGPPARANR1H2NR1H3 | |
| L-796449 SCHEMBL29361589 | 0.88 | PPARD (1.00) | PPARDPPARGPPARANR1H2NR1H3 | |
| L-796449 SCHEMBL29729365 | 0.88 | PPARD (1.00) | PPARDPPARGPPARANR1H2NR1H3 | |
| L-796449 SCHEMBL4296303 | 0.88 | PPARD (1.00) | PPARDPPARGPPARANR1H2NR1H3 | |
| SCHEMBL5535084 | 0.83 | PPARD (0.83) | PPARDPPARGPPARANR1H2NR1H3 | |
| SCHEMBL7038966 | 0.83 | PPARD (0.92) | PPARDPPARGPPARANR1H2NR1H3 | |
| SCHEMBL6558756 | 0.82 | PPARD (0.79) | PPARDPPARGPPARANR1H2NR1H3 | |
| SCHEMBL6560656 | 0.82 | PPARD (0.85) | PPARDPPARGPPARANR1H2NR1H3 | |
| L-165461 SCHEMBL6753428 | 0.82 | PPARD (1.00) | PPARDPPARGPPARANR1H2NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0904079-B1 | ANTIDIABETIC AGENTS | MERCK & CO INC (US) | 2004-03-24 | — | — | EP | disclosed |
| EP-0904079-A4 | — | — | 1999-05-06 | — | — | EP | disclosed |
| EP-0904079-A1 | ANTIDIABETIC AGENTS | Merck & Co., Inc. (US) | 1999-03-31 | — | — | EP | disclosed |
| US-5859051-A | ACETYLPHENOL DERIVATIVES | MERCK & CO., INC. (US) | 1999-01-12 | — | — | US | disclosed |
| WO-1997027857-A1 | ANTIDIABETIC AGENTS | MERCK & CO., INC. (US) | 1997-08-07 | — | — | WO | disclosed |