Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.34 |
| ▸ | NEK2 | P51955 | 1/20 | 0.34 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.34 |
| ▸ | GLI1 | P08151 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | ATP4A | P20648 | 1/20 | 0.34 |
| ▸ | ATP4B | P51164 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2903423 | 0.82 | LIPG (0.48) | LIPGCYP3A4CYP2D6SIGMAR1 | |
| SCHEMBL5223768 | 0.80 | LIPG (0.56) | LIPG | |
| SCHEMBL5499862 | 0.80 | LIPG (0.56) | LIPG | |
| SCHEMBL31122848 | 0.80 | LIPG (0.56) | LIPG | |
| SCHEMBL8676051 | 0.80 | GAA (0.39) | ARGAAMAPTALDH1A1TP53 | |
| SCHEMBL5228295 | 0.80 | LIPG (0.56) | LIPG | |
| SCHEMBL5424386 | 0.80 | LIPG (0.56) | LIPG | |
| SCHEMBL7196354 | 0.80 | AR (0.40) | ARGAAMAPTALDH1A1TP53 | |
| SCHEMBL7494585 | 0.80 | AR (0.36) | ARGAAMAPTALDH1A1TP53 | |
| SCHEMBL28796038 | 0.80 | BCHE (0.40) | ARGAAMAPTALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1132409-B1 | Catalyst systems for the Ziegler-Natta-Olefin-Polymerisation | MERCK PATENT GMBH (DE) | 2004-06-30 | — | — | EP | claimed |