Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 4/20 | 0.43 |
| ▸ | CA1 | P00915 | 4/20 | 0.43 |
| ▸ | CA9 | Q16790 | 4/20 | 0.43 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.42 |
| ▸ | PPARD | Q03181 | 5/20 | 0.40 |
| ▸ | PPARA | Q07869 | 4/20 | 0.40 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.40 |
| ▸ | TUBB | P07437 | 1/20 | 0.40 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.40 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.40 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5973952 | 0.85 | GRM2 (0.51) | KDM4EPOLBPKMMEN1MAPT | |
| SCHEMBL7232110 | 0.80 | HTR2C (0.49) | KDM4EMEN1MAPTKMT2AHTR2C | |
| SCHEMBL7232114 | 0.79 | HTR2C (0.64) | KDM4EPOLBMEN1MAPTKMT2A | |
| SCHEMBL3208936 | 0.79 | CA12 (0.38) | MEN1MAPTKMT2AHTR2CCA12 | |
| SCHEMBL3215370 | 0.79 | KDM4C (0.46) | MEN1KMT2AFGFR1PPARDPPARA | |
| SCHEMBL4401260 | 0.76 | KDM4E (0.53) | KDM4EMEN1MAPTKMT2AHTR2C | |
| SCHEMBL4397627 | 0.76 | HTR2C (0.49) | KDM4EMEN1MAPTKMT2AHTR2C | |
| SCHEMBL4397541 | 0.76 | HTR2C (0.49) | KDM4EMEN1MAPTKMT2AHTR2C | |
| SCHEMBL4499757 | 0.75 | HTR2C (0.48) | KDM4EMEN1MAPTKMT2AHTR2C | |
| Dimethylamine SCHEMBL3332584 | 0.75 | MTNR1A (0.60) | KDM4EPOLBMEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0904079-B1 | ANTIDIABETIC AGENTS | MERCK & CO INC (US) | 2004-03-24 | — | — | EP | disclosed |
| EP-0904079-A4 | — | — | 1999-05-06 | — | — | EP | disclosed |
| EP-0904079-A1 | ANTIDIABETIC AGENTS | Merck & Co., Inc. (US) | 1999-03-31 | — | — | EP | disclosed |
| US-5859051-A | ACETYLPHENOL DERIVATIVES | MERCK & CO., INC. (US) | 1999-01-12 | — | — | US | disclosed |
| WO-1997027857-A1 | ANTIDIABETIC AGENTS | MERCK & CO., INC. (US) | 1997-08-07 | — | — | WO | disclosed |