Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 12/20 | 0.51 |
| ▸ | ADORA1 | P30542 | 10/20 | 0.51 |
| ▸ | ADORA2A | P29274 | 9/20 | 0.51 |
| ▸ | ADORA2B | P29275 | 5/20 | 0.51 |
| ▸ | PRMT5 | O14744 | 4/20 | 0.34 |
| ▸ | WDR77 | Q9BQA1 | 4/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6561812 | 1.00 | ADORA3 (0.51) | ADORA3ADORA1ADORA2AADORA2BPRMT5 | |
| SCHEMBL6229115 | 0.91 | ADORA3 (0.54) | ADORA3ADORA1ADORA2AADORA2BPRMT5 | |
| SCHEMBL5534004 | 0.91 | ADORA3 (0.54) | ADORA3ADORA1ADORA2AADORA2BPRMT5 | |
| SCHEMBL6253348 | 0.91 | ADORA3 (0.54) | ADORA3ADORA1ADORA2AADORA2BPRMT5 | |
| SCHEMBL6229111 | 0.91 | ADORA3 (0.54) | ADORA3ADORA1ADORA2AADORA2BPRMT5 | |
| Gw493838 SCHEMBL7192949 | 0.86 | ADORA3 (0.60) | ADORA3ADORA1ADORA2AADORA2BPRMT5 | |
| Gw493838 SCHEMBL6935807 | 0.84 | ADORA3 (0.66) | ADORA3ADORA1ADORA2AADORA2BPRMT5 | |
| Gw493838 SCHEMBL6696560 | 0.84 | ADORA3 (0.66) | ADORA3ADORA1ADORA2AADORA2BPRMT5 | |
| Gw493838 SCHEMBL29384676 | 0.84 | ADORA3 (0.66) | ADORA3ADORA1ADORA2AADORA2BPRMT5 | |
| Gw493838 SCHEMBL6225102 | 0.84 | ADORA3 (0.66) | ADORA3ADORA1ADORA2AADORA2BPRMT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1397379-A1 | ADENOSINE DERIVATIVE IN POLYMORPH I FORM | GLAXO GROUP LIMITED (GB) | 2004-03-17 | — | — | EP | disclosed |
| WO-2002102821-A1 | ADENOSINE DERIVATIVE IN POLYMORPH I FORM | GLAXO GROUP LIMITED (GB) | 2002-12-27 | — | — | WO | disclosed |