Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 3/20 | 0.48 |
| ▸ | GCK | P35557 | 10/20 | 0.44 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6561985 | 0.93 | KCNH2 (0.51) | KCNH2GCKFFAR2SLC6A3 | |
| SCHEMBL6563673 | 0.89 | KCNH2 (0.49) | KCNH2GCKFFAR2SLC6A3 | |
| SCHEMBL2648308 | 0.86 | KCNH2 (0.49) | KCNH2GCKFFAR2 | |
| SCHEMBL2646375 | 0.85 | KCNH2 (0.46) | KCNH2GCKFFAR2 | |
| SCHEMBL3863022 | 0.85 | KCNH2 (0.46) | KCNH2GCKFFAR2 | |
| SCHEMBL2646683 | 0.85 | KCNH2 (0.46) | KCNH2GCKFFAR2 | |
| SCHEMBL2648959 | 0.85 | GCK (0.58) | KCNH2GCKFFAR2 | |
| SCHEMBL2646265 | 0.81 | FFAR2 (0.52) | KCNH2GCKFFAR2 | |
| SCHEMBL2647073 | 0.80 | KCNH2 (0.49) | KCNH2GCKFFAR2 | |
| SCHEMBL2646014 | 0.80 | KCNH2 (0.49) | KCNH2GCKFFAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1169312-B1 | GLUCOKINASE ACTIVATORS | HOFFMANN LA ROCHE (CH) | 2004-10-06 | — | — | EP | claimed |