SCHEMBL6561933

SCHEMBL6561933

CCCCCn1c(-c2ccccc2O)nc2ccccc21

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.61
HTT P42858 3/20 0.61
MAPT P10636 3/20 0.61
HPGD P15428 2/20 0.61
MAPK1 P28482 2/20 0.61
KDM4E B2RXH2 2/20 0.61
MEN1 O00255 1/20 0.61
LMNA P02545 1/20 0.61
ALOX15 P16050 1/20 0.61
TSHR P16473 1/20 0.61
NPY1R P25929 1/20 0.61
NPY2R P49146 1/20 0.61
KMT2A Q03164 1/20 0.61
HSD17B10 Q99714 1/20 0.61
TP53 P04637 3/20 0.61
TLR8 Q9NR97 3/20 0.58
SMN1; SMN2 Q16637 3/20 0.55
GAA P10253 1/20 0.55
NPSR1 Q6W5P4 1/20 0.51
SAE1 Q9UBE0 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL229426 0.90 TP53 (0.68) ALDH1A1HTTMAPTKDM4ETP53
SCHEMBL6142493 0.87 TP53 (0.65) ALDH1A1HTTMAPTKDM4ETP53
SCHEMBL11522697 0.84 ALDH1A1 (0.69) ALDH1A1HTTMAPTHPGDMAPK1
SCHEMBL10826280 0.81 PPARG (0.59) ALDH1A1HTTMAPTKDM4ETP53
SCHEMBL19775176 0.81 KDM4E (0.61) ALDH1A1HTTMAPTHPGDMAPK1
SCHEMBL10005374 0.81 TLR8 (0.71) ALDH1A1HTTHPGDKDM4EMEN1
SCHEMBL6912526 0.80 TLR8 (0.55) ALDH1A1HTTKDM4EMEN1TSHR
SCHEMBL29056764 0.80 ALDH1A1 (0.56) ALDH1A1HTTMAPTHPGDMAPK1
SCHEMBL6810630 0.80 TLR8 (0.57) ALDH1A1HTTMAPTHPGDKDM4E
SCHEMBL10834022 0.79 TLR8 (0.68) ALDH1A1HTTMAPTTSHRTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-10330744-A None JP disclosed
US-6713194-B2 ISOINDOLO(2,1-A)INDOLE SKELETON WITH AN AROMATIC RING IN THE 3 POSITION; BLUE LIGHTRONIK TECHNOLOGY INC. (TW) 2004-03-30 US disclosed
EP-1144543-B1 ELECTROLUMINESCENT QUINOLATES SOUTH BANK UNIV ENTPR LTD (GB) 2004-03-17 EP disclosed
US-20030228487-A1 Organic electroluminescence element LIGHTRONIK TECHNOLOGY INC., (TW) 2003-12-11 US disclosed
US-5928802-A ORGANOMETALLIC COMPLEX LUMINESCENT MATERIALS FOR EFFICIENTLY PRODUCING BLUE LIGHT EMISSION EASTMAN KODAK COMPANY (US) 1999-07-27 US disclosed
JP-H10330744-A NOVEL BLUE-EMITTING MATERIAL FOR ORGANIC ELECTROLUMINESCENT DEVICE EASTMAN KODAK CO 1998-12-15 JP disclosed
EP-0878529-A2 Novel blue luminescent materials for organic electroluminescent devices EASTMAN KODAK COMPANY (US) 1998-11-18 EP disclosed
US-5755999-A Blue luminescent materials for organic electroluminescent devices EASTMAN KODAK COMPANY (US) 1998-05-26 US disclosed