Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 4/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.36 |
| ▸ | F2 | P00734 | 9/20 | 0.36 |
| ▸ | NQO2 | P16083 | 1/20 | 0.33 |
| ▸ | F10 | P00742 | 8/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.32 |
| ▸ | F7 | P08709 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | PLAU | P00749 | 1/20 | 0.30 |
| ▸ | PLAT | P00750 | 1/20 | 0.30 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.30 |
| ▸ | F3 | P13726 | 1/20 | 0.30 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7677445 | 0.92 | ITGB3 (0.36) | ITGB3ITGA2BF2F10PRSS1 | |
| SCHEMBL6563705 | 0.88 | PRSS1 (0.35) | ITGB3ITGA2BF2NQO2F10 | |
| SCHEMBL6565218 | 0.87 | — | — | |
| SCHEMBL6565268 | 0.86 | F2 (0.38) | ITGB3ITGA2BF2F10PRSS1 | |
| SCHEMBL6563659 | 0.83 | ITGB3 (0.37) | ITGB3ITGA2BF2NQO2F10 | |
| SCHEMBL6562044 | 0.83 | NQO2 (0.37) | ITGB3ITGA2BF2NQO2F10 | |
| SCHEMBL7670888 | 0.83 | F2 (0.38) | ITGB3ITGA2BF2F10PRSS1 | |
| SCHEMBL6563285 | 0.82 | ITGB3 (0.39) | ITGB3ITGA2BF2NQO2F10 | |
| SCHEMBL6563331 | 0.82 | F2 (0.43) | ITGB3ITGA2BF2 | |
| SCHEMBL6563243 | 0.81 | ITGB3 (0.39) | ITGB3ITGA2BF2NQO2F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140802-B1 | SUBSTITUTED ARYL AND HETEROARYL DERIVATIVES, THEIR PRODUCTION AND THEIR USE AS MEDICINES | BOEHRINGER INGELHEIM PHARMA (DE) | 2004-03-17 | — | — | EP | disclosed |
| US-6479524-B1 | TO PROLONG THE THROMBIN TIME | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-11-12 | — | — | US | disclosed |