Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | AURKA | O14965 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | KCNH3 | Q9ULD8 | 2/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA4 | P22748 | 2/20 | 0.39 |
| ▸ | CA6 | P23280 | 2/20 | 0.39 |
| ▸ | CA7 | P43166 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6548211 | 0.84 | MEN1 (0.42) | APPRAB9ANPC1KCNH3NPY5R | |
| SCHEMBL4651692 | 0.84 | AURKA (0.45) | RAB9AAURKANPC1KCNH3JAK2 | |
| SCHEMBL4650514 | 0.83 | CA12 (0.36) | APPRAB9AAURKANPC1KCNH3 | |
| SCHEMBL9696639 | 0.81 | CA12 (0.56) | APPRAB9AAURKANPC1KCNH3 | |
| SCHEMBL4650604 | 0.78 | CA1 (0.50) | AURKAJAK2CA12CA1CA2 | |
| SCHEMBL8092217 | 0.75 | NPC1 (0.46) | RAB9AAURKANPC1SMN1; SMN2CCNA2 | |
| SCHEMBL4649895 | 0.75 | CA1 (0.47) | RAB9ANPC1CA12CA1CA2 | |
| SCHEMBL12253181 | 0.74 | NPC1 (0.61) | APPRAB9ANPC1KCNH3JAK2 | |
| SCHEMBL4649938 | 0.72 | IDH2 (0.35) | APPRAB9AAURKANPC1SMN1; SMN2 | |
| SCHEMBL8656421 | 0.70 | RHOA (0.43) | RAB9AAURKANPC1SMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1397437-A2 | BLACK DYE MIXTURES OF FIBER-REACTIVE AZO DYES AND USE THEREOF FOR DYEING MATERIAL CONTAINING HYDROXY-AND/OR CARBOXAMIDO GROUPS | DyStar Textilfarben GmbH & Co. Deutschland KG (DE) | 2004-03-17 | — | — | EP | disclosed |
| WO-2002098988-A2 | BLACK DYE MIXTURES OF FIBER-REACTIVE AZO DYES AND USE THEREOF FOR DYEING MATERIAL CONTAINING HYDROXY-AND/OR CARBOXAMIDO GROUPS | DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) | 2002-12-12 | — | — | WO | disclosed |