SCHEMBL4650604

SCHEMBL4650604

O=S(=O)(O)c1ccc(Nc2n[c]nc(F)n2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 14/20 0.50
CA2 P00918 14/20 0.50
CA9 Q16790 14/20 0.50
CA12 O43570 10/20 0.50
CA14 Q9ULX7 6/20 0.50
CA4 P22748 4/20 0.50
CA6 P23280 4/20 0.50
CA7 P43166 4/20 0.50
CA13 Q8N1Q1 3/20 0.50
CA5A P35218 3/20 0.45
CA3 P07451 2/20 0.45
SNCA P37840 2/20 0.42
AURKA O14965 2/20 0.34
AURKB Q96GD4 2/20 0.34
PLK4 O00444 1/20 0.34
STK25 O00506 1/20 0.34
RIOK3 O14730 1/20 0.34
GAK O14976 1/20 0.34
DCLK1 O15075 1/20 0.34
PDPK1 O15530 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3954363 0.89 CA1 (0.46) CA1CA2CA9CA12CA14
SCHEMBL7718746 0.89 SNCA (0.55) CA1CA2CA9CA12CA14
SCHEMBL7717605 0.87 CA12 (0.38) CA1CA2CA9CA12CA14
SCHEMBL4650680 0.85 SNCA (0.43) CA1CA2CA9CA12CA14
SCHEMBL4649895 0.85 CA1 (0.47) CA1CA2CA9CA12CA14
SCHEMBL22375908 0.83 CA1 (0.66) CA1CA2CA9CA12CA14
SCHEMBL9697589 0.83 CA1 (0.71) CA1CA2CA9CA12CA14
SCHEMBL4651485 0.82 CA9 (0.50) CA1CA2CA9CA12CA14
SCHEMBL8631904 0.81 SNCA (0.40) CA1CA2CA9CA12CA14
SCHEMBL7720137 0.81 ENPP2 (0.45) CA1CA2CA9CA12CA14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1397438-B1 DYE MIXTURES OF FIBER-REACTIVE AZODYES AND THE USE THEREOF DYSTAR TEXTILFARBEN GMBH & CO (DE) 2008-09-10 EP claimed
US-7060114-B2 Dye mixtures of fiber-reactive azo dyes and the use thereof DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 2006-06-13 US claimed
US-6946006-B2 Black dye mixtures of fiber-reactive AZO dyes and use thereof for dyeing material containing hydroxy- and/or carboxamido groups DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 2005-09-20 US claimed
US-20040148714-A1 Dye mixtures of fiber-reactive azodyes and the use thereof DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 2004-08-05 US claimed
EP-1397438-A1 DYE MIXTURES OF FIBER-REACTIVE AZODYES AND THE USE THEREOF DyStar Textilfarben GmbH & Co. Deutschland KG (DE) 2004-03-17 EP claimed
EP-1397437-A2 BLACK DYE MIXTURES OF FIBER-REACTIVE AZO DYES AND USE THEREOF FOR DYEING MATERIAL CONTAINING HYDROXY-AND/OR CARBOXAMIDO GROUPS DyStar Textilfarben GmbH & Co. Deutschland KG (DE) 2004-03-17 EP claimed
US-20030140432-A1 Black dye mixtures of fiber-reactive AZO dyes and use thereof for dyeing material containing hydroxy- and/or carboxamido groups DYSTAR COLOURS DEUTSCHLAND GMBH (DE) 2003-07-31 US claimed
WO-2002098988-A2 BLACK DYE MIXTURES OF FIBER-REACTIVE AZO DYES AND USE THEREOF FOR DYEING MATERIAL CONTAINING HYDROXY-AND/OR CARBOXAMIDO GROUPS DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 2002-12-12 WO claimed
WO-2002098989-A1 DYE MIXTURES OF FIBER-REACTIVE AZODYES AND THE USE THEREOF DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 2002-12-12 WO claimed
US-4299764-A Azo reactive dyestuffs BAYER AKTIENGESELLSCHAFT (DE) 1981-11-10 US claimed
EP-1397438-B1 DYE MIXTURES OF FIBER-REACTIVE AZODYES AND THE USE THEREOF DYSTAR TEXTILFARBEN GMBH & CO (DE) 2008-09-10 EP disclosed
US-7060114-B2 Dye mixtures of fiber-reactive azo dyes and the use thereof DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 2006-06-13 US disclosed
EP-1397439-B1 DYE MIXTURES OF FIBER-REACTIVE AZODYES AND USE THEREOF DYSTAR TEXTILFARBEN GMBH & CO (DE) 2005-11-16 EP disclosed
US-6962611-B2 Dye mixtures of fiber-reactive azodyes and use thereof DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 2005-11-08 US disclosed
US-6946006-B2 Black dye mixtures of fiber-reactive AZO dyes and use thereof for dyeing material containing hydroxy- and/or carboxamido groups DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 2005-09-20 US disclosed
EP-0681008-B1 Black mixtures of reactive azo dyes and their use for dyeing fibrous material containing hydroxy and/or carbonamide groups DYSTAR TEXTILFARBEN GMBH & CO (DE) 2001-02-14 EP disclosed
EP-0773264-A1 Process for the preparation of triphenodioxazine dyes amidated on both sides and triphenodioxazine dyes DyStar Textilfarben GmbH & Co. Deutschland KG (DE) 1997-05-14 EP disclosed
US-5559215-A Black mixture of fibre-reactive azo dyes containing essentially a navy-blue disazo dye and an orange monoazo dye, as well as novel fibre-reactive phenylazonaphthol dyes containing A 2-(2'-sufophenylamino)-4-fluoro-1,3,5-triazin-6-ylamino group HOECHST AKTIENGESELLSCHAFT (DE) 1996-09-24 US disclosed
EP-0681008-A2 Black mixtures of reactive azo dyes and their use for dyeing fibrous material containing hydroxy and/or carbonamide groups HOECHST AKTIENGESELLSCHAFT (DE) 1995-11-08 EP disclosed
US-4299764-A Azo reactive dyestuffs BAYER AKTIENGESELLSCHAFT (DE) 1981-11-10 US disclosed