SCHEMBL6562259

SCHEMBL6562259

O=C(NCCCS(=O)(=O)CCCl)Nc1ccc(S(=O)(=O)O)c2cc(S(=O)(=O)O)cc(O)c12

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TIMP3 P35625 5/20 0.42
MEN1 O00255 3/20 0.41
KMT2A Q03164 3/20 0.41
USP2 O75604 2/20 0.41
RECQL P46063 2/20 0.41
HSD17B10 Q99714 2/20 0.41
TDP1 Q9NUW8 2/20 0.41
ALDH1A1 P00352 1/20 0.41
HPSE Q9Y251 4/20 0.37
PRMT1 Q99873 2/20 0.37
ENPP3 O14638 1/20 0.37
ENTPD3 O75355 1/20 0.37
NR1I2 O75469 1/20 0.37
PRKD3 O94806 1/20 0.37
TDP2 O95551 1/20 0.37
CBX7 O95931 1/20 0.37
NSD2 O96028 1/20 0.37
ESR1 P03372 1/20 0.37
PRKCG P05129 1/20 0.37
CYP1A2 P05177 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9352829 0.94 TIMP3 (0.44) TIMP3MEN1KMT2AUSP2RECQL
SCHEMBL10943480 0.80 TIMP3 (0.48) TIMP3MEN1KMT2AUSP2RECQL
SCHEMBL6562266 0.78 NT5E (0.56) PRMT1NSD2SIRT1NT5E
SCHEMBL10945343 0.78 TIMP3 (0.47) TIMP3MEN1KMT2AUSP2RECQL
SCHEMBL11052317 0.78 TIMP3 (0.53) TIMP3MEN1KMT2AUSP2RECQL
SCHEMBL6561275 0.77 TIMP3 (0.56) TIMP3MEN1KMT2AUSP2RECQL
SCHEMBL9449398 0.77 PRMT1 (0.63) PRMT1NSD2SIRT1NT5E
SCHEMBL8417845 0.76 TIMP3 (0.53) TIMP3MEN1KMT2AUSP2RECQL
SCHEMBL9319495 0.74 KMT2A (0.56) TIMP3MEN1KMT2AUSP2RECQL
SCHEMBL9697630 0.74 NT5E (0.53) TIMP3MEN1KMT2AUSP2RECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1055710-B1 Water-soluble fibre-reactive dyestuffs, process for their preparation and their use DYSTAR TEXTILFARBEN GMBH & CO (DE) 2004-08-11 EP disclosed
US-6444794-B1 COMPLEXING WITH SUBSTRATE DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 2002-09-03 US disclosed
EP-1055710-A1 Water-soluble fibre-reactive dyestuffs, process for their preparation and their use DyStar Textilfarben GmbH & Co. Deutschland KG (DE) 2000-11-29 EP disclosed
EP-0838504-B1 Water-soluble fiber-reactive dyes, process for their preparation and the use thereof DYSTAR TEXTILFARBEN GMBH & CO (DE) 2000-06-07 EP disclosed
US-6060591-A FOR DYEING A MATERIAL CONTAINING HYDROXY OR CARBOXAMIDE GROUPS OR BOTH DY STAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND K.G. (DE) 2000-05-09 US disclosed
US-5834601-A DYEING CELLULOSE, WOOL, POLYAMIDE DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 1998-11-10 US disclosed
EP-0848042-A2 Water-soluble fiber-reactive dyes, process for their preparation and the use thereof DyStar Textilfarben GmbH & Co. Deutschland KG (DE) 1998-06-17 EP disclosed
EP-0838504-A1 Water-soluble fiber-reactive dyes, process for their preparation and the use thereof DyStar Textilfarben GmbH & Co. Deutschland KG (DE) 1998-04-29 EP disclosed
EP-0629667-B1 Water-soluble fiber-reactive dyes, process for their preparation and the use thereof HOECHST AG (DE) 1998-02-25 EP disclosed
EP-0548795-B1 Water-soluble reactive dyes, their manufacture and their use HOECHST AG (DE) 1997-07-09 EP disclosed
EP-0548792-A2 Water-soluble reactive dyes, their manufacture and their use HOECHST AKTIENGESELLSCHAFT (DE) 1993-06-30 EP disclosed
EP-0542214-A2 Water-soluble fibre-reactive dyes, process for their preparation and the use thereof HOECHST AKTIENGESELLSCHAFT (DE) 1993-05-19 EP disclosed
EP-0538785-A2 Water-soluble fiber-reactive dyes, process for their preparation and their use HOECHST AKTIENGESELLSCHAFT (DE) 1993-04-28 EP disclosed
US-5138041-A Water-soluble fiber-reactive monoazo and disazo dyestuffs having a s-triazinylamino group and three fiber-reactive groups of the vinylsulfone series HOECHST AKTIENGESELLSCHAFT (DE) 1992-08-11 US disclosed
EP-0471713-A1 WATER-SOLUBLE AZO DYES, PROCESS FOR PRODUCING THEM AND THEIR USE. HOECHST AG (DE) 1992-02-26 EP disclosed
US-5021558-A Color strength, fastness HOECHST AKTIENGESELLSCHAFT (DE) 1991-06-04 US disclosed
WO-1990013604-A1 WATER-SOLUBLE REACTIVE DYES FOR FIBRES, THEIR PREPARATION AND USE HOECHST AKTIENGESELLSCHAFT (DE) 1990-11-15 WO disclosed
WO-1990013603-A1 WATER-SOLUBLE AZO DYES, PROCESS FOR PRODUCING THEM AND THEIR USE HOECHST AKTIENGESELLSCHAFT (DE) 1990-11-15 WO disclosed
EP-0388864-A2 Water-soluble, fibre-reactive dyes, method of their preparation and use HOECHST AKTIENGESELLSCHAFT (DE) 1990-09-26 EP disclosed
EP-0377166-A1 Water-soluble, fibre-reactive dyes, methods for their preparation and their use HOECHST AKTIENGESELLSCHAFT (DE) 1990-07-11 EP disclosed