Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 3/20 | 0.63 |
| ▸ | GCK | P35557 | 16/20 | 0.52 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6561897 | 0.88 | FFAR2 (0.48) | KCNH2GCKFFAR2 | |
| SCHEMBL6561821 | 0.87 | KCNH2 (0.58) | KCNH2GCKFFAR2 | |
| SCHEMBL27712717 | 0.85 | GCK (0.71) | KCNH2GCK | |
| SCHEMBL2646671 | 0.85 | KCNH2 (0.80) | KCNH2GCKFFAR2 | |
| SCHEMBL2646508 | 0.85 | KCNH2 (0.80) | KCNH2GCKFFAR2 | |
| SCHEMBL2646380 | 0.84 | KCNH2 (0.63) | KCNH2GCK | |
| SCHEMBL2646377 | 0.84 | KCNH2 (0.63) | KCNH2GCK | |
| SCHEMBL6563797 | 0.83 | FFAR2 (0.62) | KCNH2GCKFFAR2 | |
| SCHEMBL2647800 | 0.82 | KCNH2 (0.68) | KCNH2GCK | |
| SCHEMBL2647798 | 0.82 | KCNH2 (0.68) | KCNH2GCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1169312-B1 | GLUCOKINASE ACTIVATORS | HOFFMANN LA ROCHE (CH) | 2004-10-06 | — | — | EP | claimed |