Styrene

Styrene

SCHEMBL6562348

C=C(C)C(=O)OCCCOC(=O)C(=C)C.C=Cc1ccccc1

nearest known ligand 0.50

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.50
POLB P06746 1/20 0.50
APEX1 P27695 1/20 0.50
HTT P42858 1/20 0.50
TSHR P16473 4/20 0.47
ALDH1A1 P00352 3/20 0.44
MEN1 O00255 3/20 0.41
KMT2A Q03164 3/20 0.41
THRB P10828 2/20 0.41
KDM4E B2RXH2 3/20 0.39
ELANE P08246 1/20 0.39
MAPT P10636 3/20 0.39
LMNA P02545 1/20 0.39
GAA P10253 1/20 0.39
MAPK1 P28482 1/20 0.39
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
ADORA3 P0DMS8 1/20 0.36
HPGD P15428 1/20 0.36
XBP1 P17861 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL8361059 0.94 THRB (0.47) TDP1POLBAPEX1HTTTSHR
Styrene SCHEMBL4914898 0.93 TDP1 (0.47) TDP1POLBAPEX1HTTTSHR
Styrene SCHEMBL141229 0.93 TSHR (0.55) TDP1POLBAPEX1HTTTSHR
Styrene SCHEMBL28102099 0.93 TDP1 (0.47) TDP1POLBAPEX1HTTTSHR
Styrene SCHEMBL6556236 0.93 TSHR (0.55) TDP1POLBAPEX1HTTTSHR
Styrene SCHEMBL1930527 0.91 TSHR (0.62) TDP1POLBAPEX1HTTTSHR
Styrene SCHEMBL28298814 0.91 TDP1 (0.46) TDP1POLBAPEX1HTTTSHR
Styrene SCHEMBL6762849 0.90 TSHR (0.65) TDP1POLBAPEX1HTTTSHR
Styrene SCHEMBL5444350 0.90 TSHR (0.53) TDP1POLBAPEX1HTTTSHR
Styrene SCHEMBL1984291 0.90 TSHR (0.65) TDP1POLBAPEX1HTTTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1398831-A2 Air gaps formation Shipley Co. L.L.C. (US) 2004-03-17 EP disclosed