SCHEMBL6562413

SCHEMBL6562413

CCCC(=O)Oc1ccc(-c2ccc(C(=O)O)cc2)cc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 2/20 0.62
RARB P10826 7/20 0.56
BCL9 O00512 1/20 0.54
CTNNB1 P35222 1/20 0.54
KMT2A Q03164 4/20 0.51
RAB9A P51151 1/20 0.51
TP53 P04637 1/20 0.49
TSHR P16473 1/20 0.49
ELANE P08246 1/20 0.49
SMN1; SMN2 Q16637 2/20 0.49
HPGD P15428 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
ESR1 P03372 1/20 0.49
RECQL P46063 1/20 0.49
HIF1A Q16665 1/20 0.49
ALDH1A1 P00352 1/20 0.49
LMNA P02545 1/20 0.49
MAPT P10636 1/20 0.49
HTT P42858 1/20 0.49
RXRA P19793 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6562062 0.95 BCL9 (0.58) HSD17B10RARBBCL9CTNNB1KMT2A
SCHEMBL10339826 0.94 HSD17B10 (0.55) HSD17B10RARBBCL9CTNNB1KMT2A
Hydrochloric Acid SCHEMBL6563873 0.93 BCL9 (0.57) HSD17B10RARBBCL9CTNNB1KMT2A
SCHEMBL6836918 0.89 BCL9 (0.64) HSD17B10BCL9CTNNB1KMT2ARAB9A
SCHEMBL10865643 0.88 RARB (0.67) HSD17B10RARBKMT2ATP53TSHR
SCHEMBL10865291 0.88 RARB (0.67) HSD17B10RARBKMT2ATP53TSHR
SCHEMBL9329667 0.88 RARB (0.67) HSD17B10RARBKMT2ATP53TSHR
SCHEMBL8375767 0.88 RARB (0.67) HSD17B10RARBKMT2ATP53TSHR
SCHEMBL5859109 0.88 RARB (0.67) HSD17B10RARBKMT2ATP53TSHR
SCHEMBL9717270 0.88 RARB (0.67) HSD17B10RARBKMT2ATP53TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1225212-B1 Optically active compound and liquid crystal composition containing the compound MITSUBISHI GAS CHEMICAL CO (JP) 2004-03-24 EP disclosed
US-6677475-B2 FOR USE IN LIQUID CRYSTAL DISPLAY DEVICE MITSUBISHI GAS CHEMICAL CO., INC. (JP) 2004-01-13 US disclosed
US-20020146517-A1 Optically active compound and liquid crystal composition containing the compound MITSUBISHI GAS CHEMICAL COMPANY, INC. 2002-10-10 US disclosed
EP-1225212-A1 Optically active compound and liquid crystal composition containing the compound MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2002-07-24 EP disclosed