SCHEMBL8375767

SCHEMBL8375767

CCCCCCCCC(=O)Oc1ccc(-c2ccc(C(=O)O)cc2)cc1

nearest known ligand 0.67

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
RARB P10826 10/20 0.67
TP53 P04637 1/20 0.59
TSHR P16473 1/20 0.59
PLA2G4B P0C869 5/20 0.57
KMT2A Q03164 2/20 0.57
MEN1 O00255 1/20 0.57
ALDH1A1 P00352 1/20 0.57
RARA P10276 1/20 0.57
MAPT P10636 1/20 0.57
MTOR P42345 1/20 0.57
HSD17B10 Q99714 1/20 0.55
SMN1; SMN2 Q16637 1/20 0.54
PLA2G4A P47712 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9717270 1.00 RARB (0.67) RARBTP53TSHRPLA2G4BKMT2A
SCHEMBL5859109 1.00 RARB (0.67) RARBTP53TSHRPLA2G4BKMT2A
SCHEMBL9329667 1.00 RARB (0.67) RARBTP53TSHRPLA2G4BKMT2A
SCHEMBL10865291 1.00 RARB (0.67) RARBTP53TSHRPLA2G4BKMT2A
SCHEMBL10865643 1.00 RARB (0.67) RARBTP53TSHRPLA2G4BKMT2A
Hydrochloric Acid SCHEMBL9329657 0.99 RARB (0.65) RARBTP53TSHRPLA2G4BKMT2A
Hydrochloric Acid SCHEMBL8377373 0.99 RARB (0.65) RARBTP53TSHRPLA2G4BKMT2A
SCHEMBL1615177 0.95 TP53 (0.64) RARBTP53TSHRPLA2G4BKMT2A
SCHEMBL7777446 0.95 TP53 (0.64) RARBTP53TSHRPLA2G4BKMT2A
SCHEMBL622925 0.95 TP53 (0.64) RARBTP53TSHRPLA2G4BKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0582519-A1 Liquid crystal composition, and element and device using the same Showa Shell Sekiyu Kabushiki Kaisha (JP) 1994-02-09 EP claimed
US-5891359-A FLUOROTRIESTERAROMATIC COMPOUND FOR LIQUID CRYSTALS SHOWA SHELL SEKIYU KABUSHIKI KAISHA (JP) 1999-04-06 US disclosed
US-5837163-A Liquid crystal compounds SHOWA SHELL SEKIYU K.K. (JP) 1998-11-17 US disclosed
EP-0571277-B1 Antiferroelectric liquid crystal compound SHOWA SHELL SEKIYU (JP) 1996-06-26 EP disclosed
US-5364561-A Diluent; optically tristable; electrooptics SHOWA SHELL SEKIYU KABUSHIKI KAISHA (JP) 1994-11-15 US disclosed
EP-0425366-B1 Liquid crystal compound SHOWA SHELL SEKIYU (JP) 1994-08-03 EP disclosed
EP-0418604-B1 Liquid crystal compound SHOWA SHELL SEKIYU (JP) 1994-08-03 EP disclosed
US-5320776-A Antiferroelectric liquid crystal compound SHOWA SHELL SEKIYU KABUSHIKI KAISHA (JP) 1994-06-14 US disclosed
EP-0413989-B1 Liquid crystal compounds SHOWA SHELL SEKIYU (JP) 1994-04-27 EP disclosed
EP-0571277-A1 Antiferroelectric liquid crystal compound Showa Shell Sekiyu Kabushiki Kaisha (JP) 1993-11-24 EP disclosed
US-5207946-A LIQUID CRYSTAL COMPOUNDS SHOWA SHELL SEKIYU K.K. (JP) 1993-05-04 US disclosed
EP-0244129-B1 OPTICALLY ACTIVE COMPOUND AND LIQUID CRYSTALLINE COMPOSITION AJINOMOTO CO., INC. (JP) 1992-11-11 EP disclosed
US-5130050-A LIQUID CRYSTAL COMPOUND SHOWA SHELL SEKIYO KABUSHIKI KAISHA (JP) 1992-07-14 US disclosed
US-5116531-A LIQUID CRYSTAL COMPOUND SHOWA SHELL SEKIYU K.K. (JP) 1992-05-26 US disclosed
EP-0425366-A2 Liquid crystal compound Showa Shell Sekiyu Kabushiki Kaisha (JP) 1991-05-02 EP disclosed
EP-0418604-A1 Liquid crystal compound Showa Shell Sekiyu Kabushiki Kaisha (JP) 1991-03-27 EP disclosed
EP-0413989-A2 Liquid crystal compounds Showa Shell Sekiyu Kabushiki Kaisha (JP) 1991-02-27 EP disclosed
US-4880561-A Optically active compound and liquid crystalline composition AJINOMOTO CO., INC. (JP) 1989-11-14 US disclosed