SCHEMBL6562840

SCHEMBL6562840

Cc1cc(C(=O)O)ccc1-c1ccc(O)cc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B1 P14061 2/20 0.65
RARB P10826 1/20 0.58
ADH5 P11766 2/20 0.56
ESR2 Q92731 3/20 0.55
HSD17B10 Q99714 1/20 0.53
CA12 O43570 1/20 0.52
CA1 P00915 1/20 0.52
CA2 P00918 1/20 0.52
CA3 P07451 1/20 0.52
TYR P14679 1/20 0.52
DRD1 P21728 1/20 0.52
CA4 P22748 1/20 0.52
CA6 P23280 1/20 0.52
CA5A P35218 1/20 0.52
CA7 P43166 1/20 0.52
CA9 Q16790 1/20 0.52
CA14 Q9ULX7 1/20 0.52
CA5B Q9Y2D0 1/20 0.52
KDM4E B2RXH2 1/20 0.51
ALDH1A1 P00352 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11507830 0.91 RARB (0.63) HSD17B1RARBADH5HSD17B10KDM4E
SCHEMBL7166892 0.89 HSD17B1 (0.75) HSD17B1RARBADH5ESR2HSD17B10
SCHEMBL14540358 0.89 RARB (0.61) HSD17B1RARBADH5KDM4EALDH1A1
SCHEMBL2561933 0.86 HSD17B1 (0.70) HSD17B1RARBADH5HSD17B10KDM4E
SCHEMBL4091247 0.86 HSD17B1 (0.81) HSD17B1RARBADH5ESR2HSD17B10
SCHEMBL14157048 0.85 ESR2 (0.71) HSD17B1RARBADH5ESR2ESR1
SCHEMBL29707122 0.85 ESR2 (0.58) HSD17B1RARBADH5ESR2KDM4E
SCHEMBL121338 0.85 ESR2 (0.58) HSD17B1RARBADH5ESR2KDM4E
SCHEMBL1131951 0.84 RARB (0.57) HSD17B1RARBADH5KDM4EALDH1A1
SCHEMBL2943490 0.84 BCL2L1 (0.58) HSD17B1RARBADH5HSD17B10KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113748021-B Method for producing liquid crystal polyester processed product 本州化学工业株式会社 2024-07-05 CN claimed
CN-113748021-B Method for producing liquid crystal polyester processed product 本州化学工业株式会社 2024-07-05 CN disclosed
CN-113748021-A Method for producing liquid crystal polyester processed product 本州化学工业株式会社 2021-12-03 CN disclosed
EP-1235777-B1 VITAMIN D ANALOGUES GALDERMA RES & DEV (FR) 2004-06-16 EP disclosed
US-6569504-B1 Dimers of LC-like compounds in which the monomers are linked to each other through a high birefringence moiety (dimerization linker) DISPLAYTECH, INC. 2003-05-27 US disclosed
EP-1235777-A2 VITAMIN D ANALOGUES Galderma Research & Development, S.N.C. (FR) 2002-09-04 EP disclosed
WO-2001038303-A2 VITAMIN D ANALOGUES GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) 2001-05-31 WO disclosed
US-6139771-A USEFUL IN ELECTOOPTICAL AND NON-LINEAR OPTICAL APPLICATIONS DISPLAYTECH, INC. (US) 2000-10-31 US disclosed
EP-0339987-B1 Liquid crystal compounds having naphthalene nucleus SHOWA SHELL SEKIYU (JP) 1994-06-15 EP disclosed
US-4973738-A Liquid crystal compounds having naphthalene nucleus SHOWA SHELL SEKIYU K.K. (JP) 1990-11-27 US disclosed