Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 10/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | NAAA | Q02083 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30038460 | 0.88 | TSHR (0.66) | TSHRHPGDALDH1A1CYP3A4HCAR2 | |
| SCHEMBL20261906 | 0.88 | TSHR (0.66) | TSHRHPGDALDH1A1CYP3A4HCAR2 | |
| SCHEMBL25279157 | 0.87 | TSHR (0.68) | TSHRHPGDALDH1A1CYP3A4HCAR2 | |
| SCHEMBL28057272 | 0.85 | TSHR (0.71) | TSHRHPGDALDH1A1CYP3A4HCAR2 | |
| SCHEMBL6348669 | 0.82 | TSHR (0.76) | TSHRHPGDALDH1A1CYP3A4HCAR2 | |
| SCHEMBL17868882 | 0.82 | TSHR (0.58) | TSHRHPGDALDH1A1CYP3A4THRB | |
| SCHEMBL31405830 | 0.81 | TSHR (0.60) | TSHRHPGDALDH1A1CYP3A4HCAR2 | |
| SCHEMBL7789531 | 0.81 | TSHR (0.60) | TSHRHPGDALDH1A1CYP3A4HCAR2 | |
| SCHEMBL8505774 | 0.81 | TSHR (0.60) | TSHRHPGDALDH1A1CYP3A4HCAR2 | |
| SCHEMBL30673376 | 0.80 | TSHR (0.55) | TSHRHPGDALDH1A1CYP3A4HCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1092736-B1 | Multiphase structured polymer particles, method of manufacturing same, and uses thereof | KURARAY CO (JP) | 2004-01-07 | — | — | EP | disclosed |