SCHEMBL6562964

SCHEMBL6562964

Ic1ccc(-c2ccc(I)c(-c3ccccc3)c2)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.44
MAPT P10636 3/20 0.44
KMT2A Q03164 3/20 0.44
LMNA P02545 2/20 0.44
HTT P42858 2/20 0.44
NPC1 O15118 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
APAF1 O14727 1/20 0.44
THRB P10828 1/20 0.44
XBP1 P17861 1/20 0.44
PTBP1 P26599 1/20 0.44
RAB9A P51151 1/20 0.44
GALK1 P51570 1/20 0.44
BLM P54132 1/20 0.44
SMAD3 P84022 1/20 0.44
ATM Q13315 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
ALOX5 P09917 1/20 0.40
BACE1 P56817 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4198284 0.93 MEN1 (0.48) MEN1MAPTKMT2ALMNAHTT
SCHEMBL30323756 0.93 MEN1 (0.48) MEN1MAPTKMT2ALMNAHTT
SCHEMBL3314589 0.84 BACE1 (0.44) MEN1MAPTKMT2AALOX5BACE1
SCHEMBL24656816 0.83 HPRT1 (0.53) MEN1MAPTKMT2ALMNAHTT
SCHEMBL9219608 0.82 ALDH1A1 (0.48) MEN1MAPTKMT2ALMNAHTT
SCHEMBL21164632 0.82 MEN1 (0.41) MEN1MAPTKMT2ALMNAHTT
SCHEMBL27664209 0.81 MEN1 (0.50) MEN1MAPTKMT2ALMNAHTT
SCHEMBL2197871 0.81 MEN1 (0.50) MEN1MAPTKMT2ALMNAHTT
SCHEMBL45621 0.81 ALDH1A1 (0.60) MAPTSMN1; SMN2ALOX5ALDH1A1HSD17B10
Benzene SCHEMBL28609683 0.81 ALDH1A1 (0.60) MAPTSMN1; SMN2ALOX5ALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-6293716-A None JP disclosed
EP-1122746-B1 Composition for film formation and insulating film JSR CORP (JP) 2004-09-22 EP disclosed
US-6468589-B2 A HEAT-CURED POLYETHER BASED ON A 9,9-BIS(P-HYDROXYPHENYL)-FLUORENE HAVING AT LEAST ONE ALKYL SUBSTITUENT AND A DIHYDROXY AROMATIC COMONOMER; LOW DIELECTRIC PROTECTIVE COATINGS; HEAT RESISTANCE; NONCRACKING JSR CORPORATION (JP) 2002-10-22 US disclosed
US-20010012870-A1 Composition for film formation and insulating film JSR CORPORATION (JP) 2001-08-09 US disclosed
EP-1122746-A1 Composition for film formation and insulating film JSR Corporation (JP) 2001-08-08 EP disclosed
JP-H06293716-A TERPHENYL DERIVATIVE AND ELECTROPHOTOGRAPHIC PHOTORECEPTOR USING THE SAME DAINIPPON INK & CHEM INC 1994-10-21 JP disclosed
US-4143077-A BROMINATING, THEN IODINATING M-TERPHENYL, ETHERIFYING WITH AN ALKALI METAL PHENOLATE INSTITUT FRANCAIS DU PETROLE (FR) 1979-03-06 US disclosed