Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VDR | P11473 | 4/20 | 0.83 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27568027 | 0.93 | VDR (0.71) | VDRCNR1CNR2ESR1 | |
| SCHEMBL2855063 | 0.91 | VDR (1.00) | VDRCNR1CNR2 | |
| SCHEMBL6563026 | 0.89 | VDR (0.67) | VDRCNR1CNR2 | |
| SCHEMBL27568046 | 0.88 | VDR (0.65) | VDRPTGDR2CNR1CNR2ESR1 | |
| SCHEMBL6565142 | 0.84 | VDR (0.61) | VDRPTGDR2 | |
| SCHEMBL6564192 | 0.84 | VDR (0.68) | VDR | |
| SCHEMBL2854700 | 0.84 | VDR (0.61) | VDR | |
| SCHEMBL6563028 | 0.83 | VDR (0.60) | VDR | |
| SCHEMBL6564956 | 0.82 | VDR (0.62) | VDR | |
| SCHEMBL4891909 | 0.82 | VDR (0.84) | VDRCNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6831106-B1 | Selective activity on cell proliferation and differentiation without displaying any hypercalcaemiant nature | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2004-12-14 | — | — | US | claimed |
| EP-1235777-B1 | VITAMIN D ANALOGUES | GALDERMA RES & DEV (FR) | 2004-06-16 | — | — | EP | claimed |
| EP-1235777-A2 | VITAMIN D ANALOGUES | Galderma Research & Development, S.N.C. (FR) | 2002-09-04 | — | — | EP | claimed |
| WO-2001038303-A2 | VITAMIN D ANALOGUES | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2001-05-31 | — | — | WO | claimed |