Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6561607 | 0.84 | EDNRB (0.61) | EDNRBEDNRA | |
| SCHEMBL7252235 | 0.82 | EDNRB (0.89) | EDNRBEDNRA | |
| SCHEMBL795626 | 0.82 | EDNRB (0.77) | EDNRBEDNRA | |
| SCHEMBL6561931 | 0.82 | EDNRB (0.77) | EDNRBEDNRA | |
| SCHEMBL7245599 | 0.81 | EDNRB (0.80) | EDNRBEDNRA | |
| SCHEMBL7245146 | 0.80 | EDNRB (0.88) | EDNRBEDNRA | |
| SCHEMBL7252229 | 0.79 | EDNRB (1.00) | EDNRBEDNRA | |
| SCHEMBL2350734 | 0.79 | EDNRB (0.81) | EDNRBEDNRA | |
| SCHEMBL1068402 | 0.79 | EDNRB (0.81) | EDNRBEDNRA | |
| SCHEMBL7247503 | 0.79 | EDNRB (0.70) | EDNRBEDNRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0892786-B1 | NEW CARBOXYLIC ACID DERIVATIVES, THEIR PRODUCTION AND USE | ABBOTT GMBH & CO KG (DE) | 2004-06-09 | — | — | EP | disclosed |
| US-6610691-B1 | Inhibit binding of endothelin to receptor; treating hypertension | BASF AKTIENGESELLSCHAFT (DE) | 2003-08-26 | — | — | US | disclosed |
| EP-0892786-A1 | NEW CARBOXYLIC ACID DERIVATIVES, THEIR PRODUCTION AND USE | BASF AKTIENGESELLSCHAFT (DE) | 1999-01-27 | — | — | EP | disclosed |
| WO-1997038980-A1 | NEW CARBOXYLIC ACID DERIVATIVES, THEIR PRODUCTION AND USE | BASF AKTIENGESELLSCHAFT (DE) | 1997-10-23 | — | — | WO | disclosed |