Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VDR | P11473 | 4/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6565120 | 0.89 | VDR (0.38) | VDRNR1H2NR1H3 | |
| SCHEMBL6564984 | 0.86 | VDR (0.39) | VDR | |
| SCHEMBL6564908 | 0.84 | VDR (0.38) | VDR | |
| SCHEMBL6564186 | 0.83 | VDR (0.35) | VDRNR1H2NR1H3 | |
| SCHEMBL6563017 | 0.80 | VDR (0.39) | VDRNR1H2NR1H3CYP2C9S1PR1 | |
| SCHEMBL6565124 | 0.77 | VDR (0.38) | VDRNR1H2NR1H3 | |
| SCHEMBL6564892 | 0.74 | VDR (0.38) | VDR | |
| SCHEMBL6564946 | 0.74 | VDR (0.39) | VDR | |
| SCHEMBL6562827 | 0.72 | VDR (0.35) | VDRNR1H2NR1H3 | |
| SCHEMBL6564505 | 0.71 | VDR (0.38) | VDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1235777-B1 | VITAMIN D ANALOGUES | GALDERMA RES & DEV (FR) | 2004-06-16 | — | — | EP | claimed |