Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 12/20 | 0.55 |
| ▸ | PTGS1 | P23219 | 11/20 | 0.55 |
| ▸ | PRKCZ | Q05513 | 4/20 | 0.45 |
| ▸ | PDE5A | O76074 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5693293 | 0.81 | PTGS2 (0.73) | PTGS2PTGS1PRKCZPDE5A | |
| SCHEMBL5693452 | 0.79 | PTGS2 (0.64) | PTGS2PTGS1PRKCZPDE5A | |
| SCHEMBL5693251 | 0.75 | PTGS2 (0.64) | PTGS2PTGS1PDE5A | |
| SCHEMBL5693244 | 0.75 | PTGS2 (0.64) | PTGS2PTGS1PDE5A | |
| SCHEMBL5856358 | 0.75 | PTGS1 (0.73) | PTGS2PTGS1 | |
| SCHEMBL5693286 | 0.74 | PTGS2 (0.62) | PTGS2PTGS1PDE5A | |
| SCHEMBL5693262 | 0.73 | PTGS2 (0.59) | PTGS2PTGS1PRKCZPDE5A | |
| SCHEMBL5693232 | 0.71 | PTGS2 (0.76) | PTGS2PTGS1PRKCZPDE5A | |
| SCHEMBL5693239 | 0.70 | PTGS2 (0.58) | PTGS2PTGS1PDE5A | |
| SCHEMBL5693347 | 0.70 | PTGS2 (0.66) | PTGS2PTGS1PRKCZPDE5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1083171-B1 | PYRAZOLINE DERIVATIVES, THEIR PREPARATION AND APPLICATION AS MEDICAMENTS | ESTEVE LABOR DR (ES) | 2004-04-28 | — | — | EP | claimed |