Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Decanoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.90 |
| ▸ | PPARG | P37231 | 7/20 | 0.90 |
| ▸ | PPARD | Q03181 | 7/20 | 0.90 |
| ▸ | PPARA | Q07869 | 7/20 | 0.90 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.90 |
| ▸ | TSHR | P16473 | 4/20 | 0.90 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.90 |
| ▸ | FABP4 | P15090 | 3/20 | 0.90 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.90 |
| ▸ | TLR2 | O60603 | 2/20 | 0.90 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.90 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.90 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.90 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.90 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.90 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.90 |
| ▸ | MEN1 | O00255 | 1/20 | 0.90 |
| ▸ | ESR1 | P03372 | 1/20 | 0.90 |
| ▸ | PDE4A | P27815 | 1/20 | 0.90 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.90 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Stearic Acid SCHEMBL29564580 | 1.00 | GPR84 (0.90) | GPR84PPARGPPARDPPARAHDAC11 | |
| Myristic Acid SCHEMBL30135415 | 1.00 | GPR84 (0.90) | GPR84PPARGPPARDPPARAHDAC11 | |
| Dodecanoate SCHEMBL29543706 | 1.00 | GPR84 (0.90) | GPR84PPARGPPARDPPARAHDAC11 | |
| Stearic Acid SCHEMBL29656950 | 1.00 | GPR84 (0.90) | GPR84PPARGPPARDPPARAHDAC11 | |
| Dodecanoate SCHEMBL6561600 | 1.00 | GPR84 (0.90) | GPR84PPARGPPARDPPARAHDAC11 | |
| Stearic Acid SCHEMBL30605282 | 1.00 | GPR84 (0.90) | GPR84PPARGPPARDPPARAHDAC11 | |
| Myristic Acid SCHEMBL1830813 | 1.00 | GPR84 (0.90) | GPR84PPARGPPARDPPARAHDAC11 | |
| Behenic Acid SCHEMBL6563203 | 1.00 | GPR84 (0.90) | GPR84PPARGPPARDPPARAHDAC11 | |
| Stearic Acid SCHEMBL2575032 | 1.00 | GPR84 (0.90) | GPR84PPARGPPARDPPARAHDAC11 | |
| Octanoic Acid SCHEMBL30799574 | 1.00 | GPR84 (0.90) | GPR84PPARGPPARDPPARAHDAC11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0754031-B1 | MULTILAMELLAR DRUG DELIVERY SYSTEMS | SHIRE LAB INC (US) | 2004-03-24 | — | — | EP | claimed |
| EP-0754031-A4 | MULTILAMELLAR DRUG DELIVERY SYSTEMS | PHARMAVENE INC (US) | 2000-01-19 | — | — | EP | claimed |
| EP-0750494-A4 | HYDROPHOBIC DRUG DELIVERY SYSTEMS | PHARMAVENE INC (US) | 1998-05-20 | — | — | EP | claimed |
| EP-0840611-A1 | ORAL ACYCLOVIR DELIVERY | PHARMAVENE, INC. (US) | 1998-05-13 | — | — | EP | claimed |
| EP-0788346-A4 | EMULSIFIED DRUG DELIVERY SYSTEMS | PHARMAVENE INC (US) | 1998-05-06 | — | — | EP | claimed |
| EP-0788346-A1 | EMULSIFIED DRUG DELIVERY SYSTEMS | PHARMAVENE, INC. (US) | 1997-08-13 | — | — | EP | claimed |
| EP-0754031-A1 | MULTILAMELLAR DRUG DELIVERY SYSTEMS | PHARMAVENE, INC. (US) | 1997-01-22 | — | — | EP | claimed |
| EP-0750494-A1 | HYDROPHOBIC DRUG DELIVERY SYSTEMS | PHARMAVENE, INC. (US) | 1997-01-02 | — | — | EP | claimed |
| WO-1996040144-A1 | ORAL ACYCLOVIR DELIVERY | PHARMAVENE, INC. (US) | 1996-12-19 | — | — | WO | claimed |
| WO-1996037215-A1 | ORAL INSULIN DELIVERY | PHARMAVENE, INC. (US) | 1996-11-28 | — | — | WO | claimed |
| WO-1995027479-A1 | MULTILAMELLAR DRUG DELIVERY SYSTEMS | PHARMAVENE, INC. (US) | 1995-10-19 | — | — | WO | claimed |
| WO-1995025505-A1 | HYDROPHOBIC DRUG DELIVERY SYSTEMS | PHARMAVENE, INC. (US) | 1995-09-28 | — | — | WO | claimed |
| WO-1995025504-A1 | EMULSIFIED DRUG DELIVERY SYSTEMS | PHARMAVENE, INC. (US) | 1995-09-28 | — | — | WO | claimed |
| US-5447729-A | Hydrophilic-hydrophobic layers | PHARMAVENE, INC. (US) | 1995-09-05 | — | — | US | claimed |
| CN-107922754-B | Composition for coating thermoplastic polymer film, method for producing the composition, modified thermoplastic polymer film, and method for producing the modified thermoplastic polymer film | 竹本油脂株式会社 | 2019-03-08 | — | — | CN | disclosed |
| CN-107922754-A | Composition for coating thermoplastic polymer film, method for producing composition for coating thermoplastic polymer film, modified thermoplastic polymer film, and method for producing modified thermoplastic polymer film | 竹本油脂株式会社 | 2018-04-17 | — | — | CN | disclosed |
| CN-105121550-B | Polyamide compound containing graphene | 巴斯夫欧洲公司 | 2017-11-03 | — | — | CN | disclosed |
| CN-101588792-B | Nanoemulsion | BIOFRONTERA BIOSCIENCE GMBH | 2012-03-21 | — | — | CN | disclosed |
| CN-101880703-A | Method for fermenting daptomycin by adding caprate | FUJIAN INST MICROBIOLOGY | 2010-11-10 | — | — | CN | disclosed |
| CN-1553888-A | Biphenylene compounds | �������⻯ѧƷ�ع�����˾ | 2004-12-08 | — | — | CN | disclosed |