Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 20/20 | 0.63 |
| ▸ | ITGA4 | P13612 | 20/20 | 0.63 |
| ▸ | ITGA2 | P17301 | 1/20 | 0.63 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18068435 | 0.83 | ITGB1 (0.63) | ITGB1ITGA4ITGA2ITGB7 | |
| SCHEMBL6562655 | 0.82 | ITGB1 (0.61) | ITGB1ITGA4ITGA2ITGB7 | |
| SCHEMBL6561285 | 0.81 | ITGB1 (0.59) | ITGB1ITGA4ITGA2ITGB7 | |
| SCHEMBL18068487 | 0.79 | ITGB1 (0.58) | ITGB1ITGA4ITGA2ITGB7 | |
| SCHEMBL14802063 | 0.78 | ITGB1 (1.00) | ITGB1ITGA4ITGA2ITGB7 | |
| SCHEMBL6641625 | 0.78 | ITGB1 (1.00) | ITGB1ITGA4ITGA2ITGB7 | |
| SCHEMBL480284 | 0.78 | ITGB1 (1.00) | ITGB1ITGA4ITGA2ITGB7 | |
| SCHEMBL18068339 | 0.78 | ITGB1 (0.60) | ITGB1ITGA4ITGA2ITGB7 | |
| SCHEMBL6638294 | 0.77 | ITGB1 (0.98) | ITGB1ITGA4ITGA2ITGB7 | |
| SCHEMBL5262862 | 0.77 | ITGA4 (0.70) | ITGB1ITGA4ITGA2ITGB7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1144365-B1 | INHIBITORS OF ALPHA-4 BETA-1 MEDIATED CELL ADHESION | TANABE SEIYAKU CO (JP) | 2004-03-17 | — | — | EP | disclosed |