Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.36 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.35 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6562104 | 1.00 | PLK1 (0.41) | PLK1MEN1KMT2ARXFP1SMN1; SMN2 | |
| SCHEMBL6562099 | 1.00 | PLK1 (0.41) | PLK1MEN1KMT2ARXFP1SMN1; SMN2 | |
| SCHEMBL6563174 | 0.88 | PLK1 (0.53) | PLK1MEN1KMT2ARXFP1HPGD | |
| SCHEMBL6563179 | 0.88 | PLK1 (0.53) | PLK1MEN1KMT2ARXFP1HPGD | |
| SCHEMBL6561794 | 0.85 | PLK1 (0.55) | PLK1MEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL6561798 | 0.85 | PLK1 (0.55) | PLK1MEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL6561799 | 0.85 | PLK1 (0.55) | PLK1MEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL6560678 | 0.79 | MEN1 (0.42) | PLK1MEN1KMT2ARXFP1SMN1; SMN2 | |
| SCHEMBL6561769 | 0.79 | NPC1 (0.43) | PLK1MEN1KMT2ASMN1; SMN2HPGD | |
| SCHEMBL6560689 | 0.79 | MEN1 (0.42) | PLK1MEN1KMT2ARXFP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0944581-A4 | PROCESS OF PREPARING SUBSTITUTED ACRYLAMIDES | LILLY CO ELI (US) | 2004-09-08 | — | — | EP | disclosed |
| EP-0944581-A1 | PROCESS OF PREPARING SUBSTITUTED ACRYLAMIDES | ELI LILLY AND COMPANY (US) | 1999-09-29 | — | — | EP | disclosed |
| WO-1998022429-A1 | PROCESS OF PREPARING SUBSTITUTED ACRYLAMIDES | ELI LILLY AND COMPANY (US) | 1998-05-28 | — | — | WO | disclosed |