Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 19/20 | 0.69 |
| ▸ | METAP1 | P53582 | 13/20 | 0.69 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.37 |
| ▸ | MAP1LC3A | Q9H492 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6487333 | 0.92 | METAP2 (0.69) | METAP2METAP1MAP1LC3BMAP1LC3A | |
| SCHEMBL6477769 | 0.91 | METAP2 (0.67) | METAP2METAP1MAP1LC3BMAP1LC3A | |
| SCHEMBL6488317 | 0.90 | METAP2 (0.71) | METAP2METAP1MAP1LC3BMAP1LC3A | |
| SCHEMBL6477853 | 0.90 | METAP2 (0.71) | METAP2METAP1MAP1LC3BMAP1LC3A | |
| SCHEMBL6485509 | 0.89 | METAP2 (0.76) | METAP2METAP1 | |
| SCHEMBL6477851 | 0.89 | METAP2 (0.65) | METAP2METAP1 | |
| SCHEMBL6477302 | 0.88 | METAP2 (0.62) | METAP2METAP1 | |
| SCHEMBL6477200 | 0.88 | METAP2 (0.68) | METAP2METAP1 | |
| SCHEMBL6478204 | 0.87 | METAP2 (0.76) | METAP2METAP1MAP1LC3BMAP1LC3A | |
| SCHEMBL6477449 | 0.87 | METAP2 (0.76) | METAP2METAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1272456-B1 | HYDRAZIDE AND ALKOXYAMIDE ANGIOGENESIS INHIBITORS | ABBOTT LAB (US) | 2004-10-27 | — | — | EP | claimed |