Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 7/20 | 0.48 |
| ▸ | ACACB | O00763 | 3/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6563675 | 0.99 | F10 (0.47) | F10ACACBPRSS1HPGDALDH1A1 | |
| SCHEMBL6565941 | 0.97 | F10 (0.47) | F10ACACBPRSS1HPGDALDH1A1 | |
| SCHEMBL7676583 | 0.90 | GRM5 (0.54) | ACACBHPGDITGB3ITGA2BNPC1 | |
| SCHEMBL6565248 | 0.88 | GRM5 (0.56) | HPGDALDH1A1ITGB3ITGA2B | |
| SCHEMBL5885913 | 0.87 | F10 (0.52) | F10ACACBPRSS1HPGDALDH1A1 | |
| SCHEMBL6561958 | 0.86 | ACACB (0.49) | F10ACACBPRSS1HPGDF2 | |
| Hydrochloric Acid SCHEMBL5885501 | 0.86 | F10 (0.52) | F10ACACBPRSS1HPGDALDH1A1 | |
| SCHEMBL6563119 | 0.86 | ACACB (0.49) | ACACBHPGDALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL6565351 | 0.85 | F10 (0.44) | F10ACACBPRSS1F2 | |
| SCHEMBL6563220 | 0.84 | HPGD (0.44) | F10ACACBPRSS1HPGDL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140802-B1 | SUBSTITUTED ARYL AND HETEROARYL DERIVATIVES, THEIR PRODUCTION AND THEIR USE AS MEDICINES | BOEHRINGER INGELHEIM PHARMA (DE) | 2004-03-17 | — | — | EP | disclosed |
| US-6479524-B1 | TO PROLONG THE THROMBIN TIME | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-11-12 | — | — | US | disclosed |