Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | F10 | P00742 | 5/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | KLK1 | P06870 | 1/20 | 0.40 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ACACB | O00763 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6561958 | 0.89 | ACACB (0.49) | HPGDF10PRSS1MEN1KMT2A | |
| SCHEMBL6565351 | 0.88 | F10 (0.44) | F10PRSS1HSD11B1ACACB | |
| SCHEMBL6563597 | 0.86 | F10 (0.38) | F10PRSS1ACACB | |
| SCHEMBL6565323 | 0.85 | F7 (0.38) | HPGDF10PRSS1ACACB | |
| SCHEMBL6563750 | 0.85 | F10 (0.39) | F10PRSS1HSD11B1ACACB | |
| SCHEMBL6563675 | 0.85 | F10 (0.47) | HPGDF10PRSS1MEN1KMT2A | |
| SCHEMBL6565339 | 0.84 | HPGD (0.39) | HPGDLMNATSHRMEN1KMT2A | |
| SCHEMBL6563450 | 0.84 | F10 (0.48) | HPGDF10PRSS1L3MBTL1ACACB | |
| SCHEMBL6565233 | 0.83 | ACACB (0.39) | HPGDF10PRSS1ACACB | |
| SCHEMBL7670689 | 0.83 | F10 (0.39) | F10PRSS1ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140802-B1 | SUBSTITUTED ARYL AND HETEROARYL DERIVATIVES, THEIR PRODUCTION AND THEIR USE AS MEDICINES | BOEHRINGER INGELHEIM PHARMA (DE) | 2004-03-17 | — | — | EP | disclosed |
| US-6479524-B1 | TO PROLONG THE THROMBIN TIME | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-11-12 | — | — | US | disclosed |