Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 1/20 | 0.53 |
| ▸ | FASN | P49327 | 14/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5885699 | 0.90 | ACACB (0.50) | ACACB | |
| SCHEMBL6563427 | 0.87 | ACACB (0.49) | ACACBHPGD | |
| SCHEMBL6564460 | 0.87 | ACACB (0.51) | ACACBHPGDF10 | |
| SCHEMBL6556808 | 0.81 | ACACB (0.53) | ACACBFASNPOLBHPGD | |
| SCHEMBL5885506 | 0.79 | ACACB (0.48) | ACACBHPGDF10 | |
| SCHEMBL6571802 | 0.79 | FASN (0.43) | ACACBFASNPOLBHPGD | |
| SCHEMBL5885709 | 0.79 | ACACB (0.60) | ACACBHPGD | |
| Hydrochloric Acid SCHEMBL5885815 | 0.79 | ACACB (0.47) | ACACBHPGDF10 | |
| SCHEMBL5885715 | 0.78 | ACACB (0.59) | ACACBHPGD | |
| SCHEMBL5886160 | 0.75 | ACACB (0.51) | ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140802-B1 | SUBSTITUTED ARYL AND HETEROARYL DERIVATIVES, THEIR PRODUCTION AND THEIR USE AS MEDICINES | BOEHRINGER INGELHEIM PHARMA (DE) | 2004-03-17 | — | — | EP | disclosed |
| US-6479524-B1 | TO PROLONG THE THROMBIN TIME | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-11-12 | — | — | US | disclosed |
| EP-1140802-A1 | SUBSTITUTED ARYL AND HETEROARYL DERIVATIVES, THEIR PRODUCTION AND THEIR USE AS MEDICINES | BOEHRINGER INGELHEIM KG (DE) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000035859-A1 | SUBSTITUTED ARYL AND HETEROARYL DERIVATIVES, THEIR PRODUCTION AND THEIR USE AS MEDICINES | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2000-06-22 | — | — | WO | disclosed |