Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 4/20 | 0.51 |
| ▸ | F10 | P00742 | 9/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 2/20 | 0.36 |
| ▸ | PLG | P00747 | 2/20 | 0.36 |
| ▸ | PLAU | P00749 | 1/20 | 0.36 |
| ▸ | PLAT | P00750 | 1/20 | 0.36 |
| ▸ | F7 | P08709 | 1/20 | 0.36 |
| ▸ | F3 | P13726 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5885506 | 0.91 | ACACB (0.48) | ACACBF10PRSS1HPGDTSHR | |
| Hydrochloric Acid SCHEMBL5885815 | 0.90 | ACACB (0.47) | ACACBF10PRSS1HPGDTSHR | |
| SCHEMBL6563640 | 0.89 | ACACB (0.47) | ACACBF10PRSS1HPGDMEN1 | |
| SCHEMBL6563505 | 0.87 | ACACB (0.53) | ACACBF10HPGD | |
| SCHEMBL6561958 | 0.83 | ACACB (0.49) | ACACBF10PRSS1HPGDMEN1 | |
| SCHEMBL5885699 | 0.79 | ACACB (0.50) | ACACBTSHR | |
| SCHEMBL5885709 | 0.77 | ACACB (0.60) | ACACBHPGDTSHRMEN1KMT2A | |
| SCHEMBL5885600 | 0.76 | ACACB (0.49) | ACACBF10PRSS1KMT2APLG | |
| SCHEMBL5885702 | 0.76 | ACACB (0.46) | ACACBF10PRSS1HPGDTSHR | |
| SCHEMBL5885715 | 0.76 | ACACB (0.59) | ACACBHPGDTSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140802-B1 | SUBSTITUTED ARYL AND HETEROARYL DERIVATIVES, THEIR PRODUCTION AND THEIR USE AS MEDICINES | BOEHRINGER INGELHEIM PHARMA (DE) | 2004-03-17 | — | — | EP | disclosed |
| US-6479524-B1 | TO PROLONG THE THROMBIN TIME | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-11-12 | — | — | US | disclosed |