SCHEMBL6563629

SCHEMBL6563629

O=C(C=Cc1ccccc1)Nc1cccc2ccccc12

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPV1 Q8NER1 1/20 0.73
MAOA P21397 2/20 0.71
MAOB P27338 2/20 0.71
HDAC1 Q13547 3/20 0.65
MMP1 P03956 6/20 0.65
MMP2 P08253 6/20 0.65
MMP9 P14780 6/20 0.65
EGFR P00533 7/20 0.63
CHEK1 O14757 1/20 0.57
PIM1 P11309 1/20 0.57
CDK8 P49336 1/20 0.57
GSK3B P49841 1/20 0.57
CDK7 P50613 1/20 0.57
CDK9 P50750 1/20 0.57
LIMK1 P53667 1/20 0.57
ROCK1 Q13464 1/20 0.57
CLK4 Q9HAZ1 1/20 0.57
MAPT P10636 1/20 0.57
NPSR1 Q6W5P4 1/20 0.57
HDAC3 O15379 2/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13675771 0.85 TRPV1 (0.75) TRPV1MAOAMAOBHDAC1CHEK1
SCHEMBL7662441 0.85 MAPT (0.62) TRPV1MAOAMAOBHDAC1MMP1
SCHEMBL10492424 0.85 MMP1 (0.80) MAOAMAOBHDAC1MMP1MMP2
SCHEMBL10492426 0.85 MMP1 (0.80) MAOAMAOBHDAC1MMP1MMP2
SCHEMBL6892140 0.84 KDM4E (0.65) TRPV1MAOAMAOBGSK3BMAPT
SCHEMBL6392056 0.84 KDM4E (0.65) TRPV1MAOAMAOBGSK3BMAPT
SCHEMBL11109764 0.84 MAPT (0.60) TRPV1MAOAMAOBHDAC1GSK3B
SCHEMBL30764113 0.84 KDM4E (0.65) TRPV1MAOAMAOBGSK3BMAPT
SCHEMBL13381366 0.84 KDM4E (0.65) TRPV1MAOAMAOBGSK3BMAPT
SCHEMBL31337824 0.84 KDM4E (0.65) TRPV1MAOAMAOBGSK3BMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110058473-A A kind of bimodulus electrophoretic display device (EPD) 广州奥翼电子科技股份有限公司 2019-07-26 CN claimed
CN-110095917-A A kind of bimodulus electrophoretic display device (EPD) 广州奥翼电子科技股份有限公司 2019-08-06 CN disclosed
CN-110068975-A A kind of electrophoretic display device (EPD) 广州奥翼电子科技股份有限公司 2019-07-30 CN disclosed
EP-0944581-A4 PROCESS OF PREPARING SUBSTITUTED ACRYLAMIDES LILLY CO ELI (US) 2004-09-08 EP disclosed
EP-0944581-A1 PROCESS OF PREPARING SUBSTITUTED ACRYLAMIDES ELI LILLY AND COMPANY (US) 1999-09-29 EP disclosed
WO-1998022429-A1 PROCESS OF PREPARING SUBSTITUTED ACRYLAMIDES ELI LILLY AND COMPANY (US) 1998-05-28 WO disclosed