Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 13/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.34 |
| ▸ | TMPRSS15 | P98073 | 3/20 | 0.34 |
| ▸ | F10 | P00742 | 1/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
| ▸ | F7 | P08709 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6562044 | 0.94 | NQO2 (0.37) | NQO2F2ITGB3ITGA2BTMPRSS15 | |
| SCHEMBL7676372 | 0.92 | F2 (0.43) | F2 | |
| SCHEMBL6565357 | 0.91 | F2 (0.37) | NQO2F2TMPRSS15 | |
| SCHEMBL6561682 | 0.88 | NQO2 (0.39) | NQO2F2ITGB3ITGA2BF10 | |
| SCHEMBL6563152 | 0.87 | F2 (0.43) | NQO2F2F10PRSS1 | |
| SCHEMBL6563280 | 0.86 | NQO2 (0.35) | NQO2F2ITGB3ITGA2BTMPRSS15 | |
| SCHEMBL6562287 | 0.86 | F2 (0.41) | F2ITGB3ITGA2B | |
| SCHEMBL6563331 | 0.86 | F2 (0.43) | F2ITGB3ITGA2B | |
| SCHEMBL6565347 | 0.86 | — | — | |
| SCHEMBL6563705 | 0.85 | PRSS1 (0.35) | NQO2F2ITGB3ITGA2BF10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140802-B1 | SUBSTITUTED ARYL AND HETEROARYL DERIVATIVES, THEIR PRODUCTION AND THEIR USE AS MEDICINES | BOEHRINGER INGELHEIM PHARMA (DE) | 2004-03-17 | — | — | EP | disclosed |
| US-6479524-B1 | TO PROLONG THE THROMBIN TIME | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-11-12 | — | — | US | disclosed |
| EP-1140802-A1 | SUBSTITUTED ARYL AND HETEROARYL DERIVATIVES, THEIR PRODUCTION AND THEIR USE AS MEDICINES | BOEHRINGER INGELHEIM KG (DE) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000035859-A1 | SUBSTITUTED ARYL AND HETEROARYL DERIVATIVES, THEIR PRODUCTION AND THEIR USE AS MEDICINES | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2000-06-22 | — | — | WO | disclosed |