Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 17/20 | 0.43 |
| ▸ | NQO2 | P16083 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | PLG | P00747 | 1/20 | 0.38 |
| ▸ | PLAT | P00750 | 1/20 | 0.38 |
| ▸ | PROC | P04070 | 1/20 | 0.38 |
| ▸ | HPN | P05981 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.38 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.38 |
| ▸ | SLC47A2 | Q86VL8 | 1/20 | 0.38 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6565357 | 0.90 | F2 (0.37) | F2NQO2MEN1ALDH1A1GAA | |
| SCHEMBL6562044 | 0.88 | NQO2 (0.37) | F2NQO2F10PRSS1 | |
| SCHEMBL6563633 | 0.87 | NQO2 (0.37) | F2NQO2F10PRSS1 | |
| SCHEMBL6565418 | 0.86 | MEN1 (0.33) | F2MEN1ALDH1A1GAAMAPK1 | |
| SCHEMBL6563280 | 0.86 | NQO2 (0.35) | F2NQO2MEN1ALDH1A1GAA | |
| SCHEMBL6564229 | 0.85 | F2 (0.43) | F2NQO2SLC22A2F10PLG | |
| SCHEMBL6563563 | 0.84 | SMN1; SMN2 (0.38) | F2ALDH1A1L3MBTL1F10HPN | |
| SCHEMBL6562387 | 0.82 | NQO2 (0.51) | F2NQO2MEN1ALDH1A1GAA | |
| SCHEMBL6563331 | 0.81 | F2 (0.43) | F2 | |
| SCHEMBL6563619 | 0.81 | F2 (0.41) | F2NQO2SLC22A2F10PLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140802-B1 | SUBSTITUTED ARYL AND HETEROARYL DERIVATIVES, THEIR PRODUCTION AND THEIR USE AS MEDICINES | BOEHRINGER INGELHEIM PHARMA (DE) | 2004-03-17 | — | — | EP | disclosed |
| US-6479524-B1 | TO PROLONG THE THROMBIN TIME | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-11-12 | — | — | US | disclosed |