Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F7 | P08709 | 5/20 | 0.36 |
| ▸ | F3 | P13726 | 4/20 | 0.36 |
| ▸ | F10 | P00742 | 12/20 | 0.36 |
| ▸ | F2 | P00734 | 11/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 7/20 | 0.36 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.35 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.34 |
| ▸ | PLG | P00747 | 1/20 | 0.34 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.33 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6563600 | 0.91 | F7 (0.39) | F7F3F10F2PRSS1 | |
| SCHEMBL6561947 | 0.88 | F10 (0.36) | F7F3F10F2PRSS1 | |
| SCHEMBL6564919 | 0.86 | PTPN11 (0.35) | — | |
| SCHEMBL6563363 | 0.85 | F2 (0.38) | F7F3F10F2PRSS1 | |
| SCHEMBL6565922 | 0.83 | F7 (0.39) | F7F3F10F2ITGB3 | |
| SCHEMBL6563127 | 0.82 | F2 (0.37) | F7F3F10F2PRSS1 | |
| SCHEMBL7799479 | 0.82 | NR1I2 (0.36) | F2 | |
| SCHEMBL7799478 | 0.82 | MEN1 (0.31) | — | |
| SCHEMBL6563782 | 0.81 | F2 (0.41) | F7F10F2PRSS1ITGB3 | |
| SCHEMBL6565187 | 0.81 | F10 (0.34) | F7F3F10F2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140802-B1 | SUBSTITUTED ARYL AND HETEROARYL DERIVATIVES, THEIR PRODUCTION AND THEIR USE AS MEDICINES | BOEHRINGER INGELHEIM PHARMA (DE) | 2004-03-17 | — | — | EP | disclosed |
| US-6479524-B1 | TO PROLONG THE THROMBIN TIME | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-11-12 | — | — | US | disclosed |