Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ACACB | O00763 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7806874 | 0.86 | KDM4E (0.31) | — | |
| SCHEMBL6563647 | 0.82 | F7 (0.36) | — | |
| SCHEMBL7799479 | 0.81 | NR1I2 (0.36) | MEN1GAAMAPTHTTKMT2A | |
| SCHEMBL7806157 | 0.74 | MEN1 (0.38) | MEN1GAAKMT2A | |
| SCHEMBL6563600 | 0.73 | F7 (0.39) | — | |
| SCHEMBL6564919 | 0.72 | PTPN11 (0.35) | ACACB | |
| SCHEMBL6563363 | 0.72 | F2 (0.38) | MAPT | |
| SCHEMBL7804873 | 0.71 | TSHR (0.44) | MEN1GAAMAPTHTTKMT2A | |
| SCHEMBL6561947 | 0.71 | F10 (0.36) | — | |
| SCHEMBL7675036 | 0.70 | F10 (0.42) | MEN1GAAMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140802-A1 | SUBSTITUTED ARYL AND HETEROARYL DERIVATIVES, THEIR PRODUCTION AND THEIR USE AS MEDICINES | BOEHRINGER INGELHEIM KG (DE) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000035859-A1 | SUBSTITUTED ARYL AND HETEROARYL DERIVATIVES, THEIR PRODUCTION AND THEIR USE AS MEDICINES | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2000-06-22 | — | — | WO | disclosed |