Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.49 |
| ▸ | ACACB | O00763 | 1/20 | 0.48 |
| ▸ | HCRTR1 | O43613 | 5/20 | 0.44 |
| ▸ | FASN | P49327 | 6/20 | 0.44 |
| ▸ | DPP4 | P27487 | 5/20 | 0.43 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.43 |
| ▸ | CCNK | O75909 | 1/20 | 0.41 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6563234 | 0.86 | ACACB (0.46) | DPP7ACACBFASN | |
| SCHEMBL5885749 | 0.81 | ACACB (0.48) | ACACB | |
| SCHEMBL5885759 | 0.81 | ACACB (0.48) | ACACBFASN | |
| SCHEMBL6563806 | 0.79 | ACACB (0.52) | ACACB | |
| SCHEMBL6556808 | 0.78 | ACACB (0.53) | ACACBFASN | |
| SCHEMBL5885873 | 0.76 | ACACB (0.57) | ACACB | |
| SCHEMBL6563753 | 0.75 | ACACB (0.56) | ACACB | |
| SCHEMBL6563935 | 0.75 | ACACB (0.48) | ACACBFASN | |
| SCHEMBL5885408 | 0.74 | ACACB (0.46) | ACACBHCRTR1 | |
| SCHEMBL6561958 | 0.74 | ACACB (0.49) | ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140802-B1 | SUBSTITUTED ARYL AND HETEROARYL DERIVATIVES, THEIR PRODUCTION AND THEIR USE AS MEDICINES | BOEHRINGER INGELHEIM PHARMA (DE) | 2004-03-17 | — | — | EP | disclosed |
| US-6479524-B1 | TO PROLONG THE THROMBIN TIME | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-11-12 | — | — | US | disclosed |
| EP-1140802-A1 | SUBSTITUTED ARYL AND HETEROARYL DERIVATIVES, THEIR PRODUCTION AND THEIR USE AS MEDICINES | BOEHRINGER INGELHEIM KG (DE) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000035859-A1 | SUBSTITUTED ARYL AND HETEROARYL DERIVATIVES, THEIR PRODUCTION AND THEIR USE AS MEDICINES | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2000-06-22 | — | — | WO | disclosed |