Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 1/20 | 0.50 |
| ▸ | L3MBTL3 | Q96JM7 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 6/20 | 0.37 |
| ▸ | MTOR | P42345 | 6/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | FASN | P49327 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 2/20 | 0.36 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6563697 | 1.00 | ACACB (0.50) | ACACBL3MBTL3L3MBTL1HPGDPIK3CA | |
| SCHEMBL5885873 | 0.78 | ACACB (0.57) | ACACBL3MBTL3L3MBTL1HPGDHTT | |
| SCHEMBL6563753 | 0.77 | ACACB (0.56) | ACACBL3MBTL3L3MBTL1HPGDPIK3CA | |
| SCHEMBL5885712 | 0.75 | ACACB (0.54) | ACACBL3MBTL3L3MBTL1HPGDHTT | |
| SCHEMBL6563806 | 0.74 | ACACB (0.52) | ACACBHPGDPIK3CAMTORHTT | |
| SCHEMBL6561958 | 0.74 | ACACB (0.49) | ACACBHPGDKMT2A | |
| SCHEMBL5885759 | 0.71 | ACACB (0.48) | ACACBHPGDFASNHTT | |
| SCHEMBL5885749 | 0.71 | ACACB (0.48) | ACACB | |
| SCHEMBL5885702 | 0.71 | ACACB (0.46) | ACACBHPGDHTTKMT2A | |
| SCHEMBL5885818 | 0.71 | ACACB (0.46) | ACACBHPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140802-B1 | SUBSTITUTED ARYL AND HETEROARYL DERIVATIVES, THEIR PRODUCTION AND THEIR USE AS MEDICINES | BOEHRINGER INGELHEIM PHARMA (DE) | 2004-03-17 | — | — | EP | disclosed |
| US-6479524-B1 | TO PROLONG THE THROMBIN TIME | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-11-12 | — | — | US | disclosed |