Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 11/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 6/20 | 0.39 |
| ▸ | ACACB | O00763 | 3/20 | 0.39 |
| ▸ | F7 | P08709 | 3/20 | 0.36 |
| ▸ | F3 | P13726 | 3/20 | 0.36 |
| ▸ | F2 | P00734 | 4/20 | 0.35 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.35 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6563672 | 0.91 | ACACB (0.38) | F10PRSS1ACACBF2ALDH1A1 | |
| SCHEMBL6563220 | 0.85 | HPGD (0.44) | F10PRSS1ACACBHSD11B1 | |
| SCHEMBL6561958 | 0.84 | ACACB (0.49) | F10PRSS1ACACBF7F3 | |
| SCHEMBL6565351 | 0.83 | F10 (0.44) | F10PRSS1ACACBF7F3 | |
| SCHEMBL6565323 | 0.81 | F7 (0.38) | F10PRSS1ACACBF7F3 | |
| SCHEMBL6563597 | 0.81 | F10 (0.38) | F10PRSS1ACACBF7F3 | |
| SCHEMBL6565233 | 0.80 | ACACB (0.39) | F10PRSS1ACACBF7F3 | |
| SCHEMBL7670689 | 0.80 | F10 (0.39) | F10PRSS1ACACBF7F3 | |
| SCHEMBL6563675 | 0.79 | F10 (0.47) | F10PRSS1ACACBALDH1A1 | |
| SCHEMBL6564205 | 0.79 | F10 (0.36) | F10PRSS1ACACBF7F3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140802-B1 | SUBSTITUTED ARYL AND HETEROARYL DERIVATIVES, THEIR PRODUCTION AND THEIR USE AS MEDICINES | BOEHRINGER INGELHEIM PHARMA (DE) | 2004-03-17 | — | — | EP | disclosed |
| US-6479524-B1 | TO PROLONG THE THROMBIN TIME | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-11-12 | — | — | US | disclosed |