SCHEMBL6563766

SCHEMBL6563766

C=C(C)C(=O)OCCC(=O)Oc1ccc(C(C)(C)c2ccc(OC(=O)CCOC(=O)C(=C)C)cc2)cc1

nearest known ligand 0.55

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HTT P42858 3/20 0.43
POLB P06746 2/20 0.43
APEX1 P27695 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
KMT2A Q03164 5/20 0.41
ALDH1A1 P00352 4/20 0.41
LMNA P02545 1/20 0.41
MAPT P10636 1/20 0.41
HSD17B10 Q99714 1/20 0.41
ELANE P08246 1/20 0.38
THRB P10828 1/20 0.37
KDM4E B2RXH2 4/20 0.36
TSHR P16473 2/20 0.36
ATM Q13315 1/20 0.36
MEN1 O00255 1/20 0.36
AR P10275 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.35
BCL9 O00512 1/20 0.35
CTNNB1 P35222 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15500114 0.90 HTT (0.51) HTTPOLBAPEX1TDP1KMT2A
SCHEMBL25784280 0.88 TDP1 (0.44) HTTPOLBAPEX1TDP1KMT2A
SCHEMBL16806094 0.86 POLB (0.45) HTTPOLBAPEX1TDP1KMT2A
SCHEMBL6290863 0.84 POLB (0.44) HTTPOLBAPEX1TDP1KMT2A
SCHEMBL22142657 0.84 KMT2A (0.49) HTTPOLBAPEX1TDP1KMT2A
SCHEMBL14173145 0.84 HTT (0.46) HTTPOLBAPEX1TDP1KMT2A
SCHEMBL15500172 0.84 POLB (0.46) HTTPOLBAPEX1TDP1KMT2A
SCHEMBL6668640 0.83 POLB (0.56) HTTPOLBAPEX1TDP1KMT2A
SCHEMBL16351988 0.83 ELANE (0.47) HTTPOLBAPEX1TDP1KMT2A
SCHEMBL20079353 0.83 ELANE (0.46) HTTPOLBAPEX1TDP1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0972805-B1 Polyimide-based composite, electronic parts using the composite, and polyimide-based aqueous dispersion JSR CORP (JP) 2004-11-17 EP disclosed
US-6214923-B1 POLYIMIDE COMPONENT AND OTHER POLYMER IN THE SAME PARTICLE IN DISPERSION TO IMPROVE STORAGE STABILITY; IN COMPOSITE, POLYIMIDE FORMS CONTINUOUS PHASE AND POLYMER DISCONTINUOUS PHASE, LOW ELASTIC MODULUS; HEAT RESISTANCE JSR CORPORATION (JP) 2001-04-10 US disclosed
EP-0972805-A2 Polyimide-based composite, electronic parts using the composite, and polyimide-based aqueous dispersion JSR Corporation (JP) 2000-01-19 EP disclosed