Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.59 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.59 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.50 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.50 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.50 |
| ▸ | GRIA3 | P42263 | 2/20 | 0.50 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.50 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.50 |
| ▸ | GRIK3 | Q13003 | 2/20 | 0.50 |
| ▸ | GRIK4 | Q16099 | 2/20 | 0.50 |
| ▸ | GRIK5 | Q16478 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30657601 | 1.00 | ESR1 (0.59) | ESR1ESR2GRIK1GRIA1GRIA2 | |
| SCHEMBL6677996 | 0.81 | GAA (0.57) | GRIK1GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL28850718 | 0.80 | GRIA1 (0.56) | ESR1ESR2GRIK1GRIA1GRIA2 | |
| SCHEMBL29126960 | 0.79 | GRIK1 (0.50) | ESR1ESR2GRIK1GRIA1GRIA2 | |
| SCHEMBL29721807 | 0.79 | TSHR (0.56) | GRIK1GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL27420986 | 0.79 | GRIK1 (0.50) | ESR1ESR2GRIK1GRIA1GRIA2 | |
| SCHEMBL11824811 | 0.79 | MAPK1 (0.59) | GRIK1GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL9044798 | 0.79 | TSHR (0.56) | GRIK1GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL20816305 | 0.79 | TDP1 (0.50) | ESR1ESR2GRIK1GRIA1GRIA2 | |
| SCHEMBL3790185 | 0.79 | MAPT (0.55) | GRIK1GRIA1GRIA2GRIA3GRIA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117143104-A | Pyrrolo [1,2-a ] quinoxaline compound synthesized from nitropyrrole aromatic hydrocarbon and carbon dioxide and synthesis method thereof | 陕西科技大学 | 2023-12-01 | — | — | CN | claimed |
| EP-1304994-B1 | PYRROLYL-SUBSTITUTED NITROPHENOLS USED AS DIRECT COLORANTS | HENKEL KGAA (DE) | 2004-10-20 | — | — | EP | claimed |
| EP-1304994-A1 | PYRROLYL-SUBSTITUTED NITROPHENOLS USED AS DIRECT COLORANTS | Henkel Kommanditgesellschaft auf Aktien (DE) | 2003-05-02 | — | — | EP | claimed |
| WO-2002009661-A1 | PYRROLYL-SUBSTITUTED NITROPHENOLS USED AS DIRECT COLORANTS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2002-02-07 | — | — | WO | claimed |
| CN-117143104-A | Pyrrolo [1,2-a ] quinoxaline compound synthesized from nitropyrrole aromatic hydrocarbon and carbon dioxide and synthesis method thereof | 陕西科技大学 | 2023-12-01 | — | — | CN | disclosed |
| US-10973819-B2 | Small molecules inhibitors of RAD51 | THE UNIVERSITY OF CHICAGO (US) | 2021-04-13 | — | — | US | disclosed |
| US-20190083491-A1 | SMALL MOLECULES INHIBITORS OF RAD51 | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2019-03-21 | — | — | US | disclosed |
| EP-1304994-B1 | PYRROLYL-SUBSTITUTED NITROPHENOLS USED AS DIRECT COLORANTS | HENKEL KGAA (DE) | 2004-10-20 | — | — | EP | disclosed |
| EP-1304994-A1 | PYRROLYL-SUBSTITUTED NITROPHENOLS USED AS DIRECT COLORANTS | Henkel Kommanditgesellschaft auf Aktien (DE) | 2003-05-02 | — | — | EP | disclosed |
| WO-2002009661-A1 | PYRROLYL-SUBSTITUTED NITROPHENOLS USED AS DIRECT COLORANTS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2002-02-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190083491-A1 | SMALL MOLECULES INHIBITORS OF RAD51 | RAD51, MRE11, DDB1 | ESR1 2108/4885ESR2 2558/4885GRIK1 4617/4885 |
| US-10973819-B2 | Small molecules inhibitors of RAD51 | RAD51, MRE11, DDB1 | ESR1 2108/4885ESR2 2558/4885GRIK1 4617/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.