SCHEMBL6563882

SCHEMBL6563882

O=C(OCl)c1ccc(Cl)c(Cl)c1Cl

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.39
MAPK1 P28482 1/20 0.39
TSHR P16473 2/20 0.38
ABL1 P00519 1/20 0.35
GPR27 Q9NS67 1/20 0.35
KMT2A Q03164 2/20 0.34
ATM Q13315 1/20 0.34
ALPL P05186 1/20 0.34
ALDH1A1 P00352 2/20 0.33
TP53 P04637 1/20 0.33
MAPT P10636 1/20 0.33
ALOX12 P18054 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
CASP1 P29466 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
CSNK2A2 P19784 1/20 0.33
CSNK2B P67870 1/20 0.33
CSNK2A1 P68400 1/20 0.33
CES2 O00748 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5030228 0.84 CYP3A4 (0.41) CYP3A4MAPK1TSHRGPR27KMT2A
SCHEMBL20513001 0.84 CYP3A4 (0.41) CYP3A4MAPK1TSHRGPR27KMT2A
SCHEMBL8470866 0.83 TSHR (0.35) CYP3A4MAPK1TSHRABL1KMT2A
SCHEMBL30360858 0.83 CYP3A4 (0.39) CYP3A4MAPK1TSHRGPR27KMT2A
SCHEMBL28167039 0.83 CYP3A4 (0.39) CYP3A4MAPK1TSHRGPR27KMT2A
SCHEMBL27362505 0.81 ABL1 (0.50) MAPK1TSHRABL1KMT2AATM
SCHEMBL23318194 0.76 STAT3 (0.38) CYP3A4MAPK1TSHRKMT2AALPL
SCHEMBL27259744 0.76 CYP4F2 (0.55) MAPK1TSHRKMT2AALDH1A1MAPT
SCHEMBL29886586 0.75 TSHR (0.64) CYP3A4MAPK1TSHRGPR27KMT2A
SCHEMBL4452322 0.75 MAPK1 (0.44) CYP3A4MAPK1TSHRGPR27KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1152287-B1 Asymmetric silver salt dimers and imaging compositions, materials and methods using same EASTMAN KODAK CO (US) 2004-03-31 EP disclosed
US-6566045-B1 Useful in thermally-developable imaging materials including thermographic and photothermographic materials EASTMAN KODAK COMPANY 2003-05-20 US disclosed
US-6472131-B1 Asymmetric silver salt dimers and imaging compositions, materials and methods using same EASTMAN KODAK COMPANY 2002-10-29 US disclosed
EP-1152287-A2 Asymmetric silver salt dimers and imaging compositions, materials and methods using same EASTMAN KODAK COMPANY (US) 2001-11-07 EP disclosed