Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 14/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 9/20 | 0.54 |
| ▸ | CFTR | P13569 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 5/20 | 0.43 |
| ▸ | HPGD | P15428 | 5/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27146814 | 0.81 | ALDH1A1 (0.60) | ALDH1A1HSD17B10CFTRKDM4EPOLB | |
| SCHEMBL6563889 | 0.78 | ALDH1A1 (0.53) | ALDH1A1HSD17B10CFTRKDM4EPOLB | |
| SCHEMBL8546366 | 0.75 | ALDH1A1 (0.60) | ALDH1A1HSD17B10CFTRKDM4EPOLB | |
| SCHEMBL29851692 | 0.74 | ALDH1A1 (0.63) | ALDH1A1HSD17B10CFTRKDM4EPOLB | |
| SCHEMBL171563 | 0.74 | ALDH1A1 (0.63) | ALDH1A1HSD17B10CFTRKDM4EPOLB | |
| SCHEMBL28280199 | 0.73 | ALDH1A1 (0.62) | ALDH1A1HSD17B10CFTRKDM4EPOLB | |
| SCHEMBL11769004 | 0.73 | TSHR (0.47) | ALDH1A1HSD17B10TSHRNPC1TP53 | |
| SCHEMBL11023805 | 0.73 | ALDH1A1 (0.66) | ALDH1A1HSD17B10CFTRKDM4EPOLB | |
| SCHEMBL29024770 | 0.73 | ALDH1A1 (0.61) | ALDH1A1HSD17B10CFTRKDM4EPOLB | |
| SCHEMBL3110030 | 0.72 | ALDH1A1 (0.60) | ALDH1A1HSD17B10CFTRKDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040234592-A1 | Mixture containing thyroid hormone , ethanolamine and emulsifier | KARO BIO AB (SE) | 2004-11-25 | — | — | US | claimed |
| EP-1404413-A2 | DERMATOLOGICAL FORMULATIONS | KARO BIO AB (SE) | 2004-04-07 | — | — | EP | claimed |
| WO-2002089917-A2 | DERMATOLOGICAL FORMULATIONS | KARO BIO AB (SE) | 2002-11-14 | — | — | WO | claimed |
| US-20040234592-A1 | Mixture containing thyroid hormone , ethanolamine and emulsifier | KARO BIO AB (SE) | 2004-11-25 | — | — | US | disclosed |
| EP-1404413-A2 | DERMATOLOGICAL FORMULATIONS | KARO BIO AB (SE) | 2004-04-07 | — | — | EP | disclosed |
| WO-2002089917-A2 | DERMATOLOGICAL FORMULATIONS | KARO BIO AB (SE) | 2002-11-14 | — | — | WO | disclosed |